Results 211 to 220 of about 1,244,170 (347)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Research on Regional Variations in Potato Price Fluctuations and Inter-Regional Transmission Mechanisms in China. [PDF]

Foods
Lu H, Li T, Hao R, Liu Z, Gao M, Chen J.
europepmc   +1 more source

Time-domain Geoacoustic Inversion of Short-range Acoustic Data with Fluctuating Arrivals [PDF]

, 2013
Park
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Stochasticity in mammalian cell growth rates drives cell-to-cell variability independently of cell size and divisions. [PDF]

Proc Natl Acad Sci U S A
Levien E, Kang JH, Biswas K, Manalis SR, Amir A, Miettinen TP.   +5 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Lost in Projection? Gaussian Filtering Recovers Hidden Conformational States. [PDF]

J Phys Chem Lett
Sartore S, Nagel D, Diez G, Stock G.
europepmc   +1 more source

Employment fluctuations in a dynamic model with long-term and short-term contracts [PDF]

, 2019
Toyoki Matsue
openalex  

Effect of fluctuate lighting on performance of laying hens (Short Communication) [PDF]

, 2009
İsmail Durmuş, Süleyman Kalebaşı
openalex   +1 more source

Short-period fluctuations in solar activity.

The Astronomical Journal, 1955
openaire   +1 more source