Results 21 to 30 of about 283,388 (253)
CoLoRMap: Correcting Long Reads by Mapping short reads [PDF]
Bioinformatics, 2016 Abstract Motivation Second generation sequencing technologies paved the way to an exceptional increase in the number of sequenced genomes, both prokaryotic and eukaryotic. However, short reads are difficult to assemble and often lead to highly fragmented assemblies.
Ehsan Haghshenas +3 more
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BMC Genomics, 2021 Background SNP arrays, short- and long-read genome sequencing are genome-wide high-throughput technologies that may be used to assay copy number variants (CNVs) in a personal genome.
Ksenia Lavrichenko +2 more
doaj +1 more source
NucBase, an easy to use read mapper for small RNAs
Mobile DNA, 2013 Background High-throughput deep-sequencing technology has generated an unprecedented number of expressed sequence reads that offer the opportunity to get insight into biological systems.
Dufourt Jeremy +4 more
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A short presidential reading list [PDF]
Science, 2016 A new U.S. president will be sworn into office in less than 3 months. Because scientific issues cut across many aspects of modern life, in both the public and private sectors, the president has several challenges. He or she must ensure that the government has access to robust advice about scientific issues to guide policy development.
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Evaluation of short read metagenomic assembly [PDF]
2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2010 Metagenomic assembly is a challenging problem due to the presence of genetic material from multiple organisms. The problem becomes even more difficult when short reads produced by next generation sequencing technologies are used. Although whole genome assemblers are not designed to assemble metagenomic samples, they are being used for metagenomics due ...
Anveshi Charuvaka, Huzefa Rangwala
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Towards reliable whole genome sequencing for outbreak preparedness and response
BMC Genomics, 2022 Background To understand the dynamics of infectious diseases, genomic epidemiology is increasingly advocated, with a need for rapid generation of genetic sequences during outbreaks for public health decision making.
David F. Nieuwenhuijse +5 more
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An analysis of the feasibility of short read sequencing [PDF]
Nucleic Acids Research, 2005 Several methods for ultra high-throughput DNA sequencing are currently under investigation. Many of these methods yield very short blocks of sequence information (reads). Here we report on an analysis showing the level of genome sequencing possible as a function of read length.
Whiteford, N. +7 more
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Determination of the Optimum Number of Short Reads to Obtain the Mitogenome in some Insect Orders
Cumhuriyet Science Journal, 2023 Sanger sequencing is frequently used as the final step in time-consuming extraction and enrichment processes for examining the mitochondrial genome (mitogenome).
Mahir Budak
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Microorganisms, 2021 In 2013, the U.S. Department of Agriculture Food Safety and Inspection Service (USDA-FSIS) began transitioning to whole genome sequencing (WGS) for foodborne disease outbreak- and recall-associated isolate identification of select bacterial species ...
Dustin A. Therrien +9 more
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Short read alignment with populations of genomes [PDF]
Bioinformatics, 2013 Abstract Summary: The increasing availability of high-throughput sequencing technologies has led to thousands of human genomes having been sequenced in the past years. Efforts such as the 1000 Genomes Project further add to the availability of human genome variation data. However, to date, there is no method that can map reads of a newly
Lin Huang +2 more
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