Results 111 to 120 of about 6,463,650 (307)

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Kinerja Rantai Pasok Kedelai di Kabupaten Grobogan

Jurnal Aplikasi Bisnis dan Manajemen, 2018
The objectives of this study were to illustrate the structure of the soybean supply chain, to identify the performance of the soybean supply chain, and to recommend improvements in the form of managerial implications.
Bubun Bubun, Sukardi Sukardi, Ono Suparno   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transportation: A Global Supply Chain Perspective [PDF]

, 2020
Equip students with an understanding of what may be the most critical and complex component of global supply chains with TRANSPORTATION: A SUPPLY CHAIN PERSPECTIVE, 9E.
Gibson, Brian, Suzuki, Yoshinori, Novack, Robert, Coyle, John   +3 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Risk Mitigation Strategies in Supply Chain, Using 1-P Analysis and MADM A Case Study: Alloy Steel Industry [PDF]

بهبود مدیریت, 2012
In the last few years, supply chain management has become more important, because of the globalization of business. Factors such as short product life cycle, new technologies and product development have led to increase complexity in supply chain.
Seyyed Habibollah Mir Ghafoori, Faezeh Asadian Ardakani   +1 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Multi-echelon inventory modeling and supply redesign

, 2017
Thesis: M. Eng. in Supply Chain Management, Massachusetts Institute of Technology, Supply Chain Management Program, 2017.Cataloged from PDF version of thesis.Includes bibliographical references (pages 46-49).Many businesses struggle to optimize the flow ...
Scott, Patrick (Patrick James), Xu, Boxi
core  

E-commerce based closed-loop supply chain for plastic recycling

, 2020
Thesis: M. Eng. in Supply Chain Management, Massachusetts Institute of Technology, Supply Chain Management Program, May, 2020Cataloged from the official PDF of thesis.Includes bibliographical references (pages 73-77).The world is facing a grave plastic ...
Banerjee, Saikat,M. Eng.Massachusetts Institute of Technology.
core  

Financing Newsvendor with Trade Credit and Bank Credit Portfolio

Mathematics
Trade credit is a crucial component of supply chain financing, enabling businesses to manage cash flow and optimize inventory levels. This study delves into the application and implications of multiple trade credit types with different repayment periods ...
Yue Zhang, Bin Zhang, Rongguang Chen
doaj   +1 more source