Results 91 to 100 of about 154,252 (307)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Short-term debt for long-term use and default risk of supply chain enterprises.

, 2023
Short-term debt for long-term use and default risk of supply chain enterprises.
Huaqiao Shen (17271170), Jinlong Chen (1333647)   +1 more
core   +1 more source

Koordinasi Supply Chain Satu Pabrik-Satu Distributor pada Model Penentuan Harga dan Keputusan Produksi

Jurnal Teknik Industri, 2012
Competition and global market induce enterprises to meet their customer needs on product/ service in considerably cheap price, in acceptable quality and within short lead time.
Evi Yuliawati
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inovação Social e Tecnologia Social. O Caso da Cadeia Curta de Agricultores Familiares e a Alimentação Escolar em Porto Alegre/RS

Desenvolvimento em Questão, 2016
In the global scenario, social and environmental problems are challenges that mobilize the searchfor alternatives to the current paradigm, such as social innovation and social technology.
Gabriel Borela Franzoni, Tania Nunes da Silva   +1 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Optimization and Benefit Assessment of Production Supply Chain Networks Using Graph Neural Network Models

Journal of Computing and Information Technology
With the flourishing development of global economy, effective management of production supply chains is crucial for the competitiveness of enterprises. Optimizing supply chain networks can not only improve the efficiency of resource allocation but also ...
Ting Dong, Mary Jane C. Samonte
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Innovative adoption of hybrid supply chain strategies in urban local fresh food supply chain

, 2019
Purpose: This paper aims to investigate the characteristics of demand and supply in relation to the real-world supply chain strategies of local urban fresh food supply chains (FFSC).
Nakandala, Dilupa (R16707), Lau, Henry C. W. (R16009)   +1 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source