Results 61 to 70 of about 6,463,650 (307)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Building the resilient supply chain. [PDF]
, 2004 In today’s uncertain and turbulent markets, supply chain vulnerability has become an issue of significance for many companies. As supply chains become more complex as a result of global sourcing and the continued trend to ‘leaning-down’, supply chain ...
Christopher, Martin +5 more
core +1 more source
Short food supply chain: estado da arte na academia brasileira
Estudos Sociedade e Agricultura, 2016 O surgimento das Short Food Supply Chains (SFSCs) é decorrente da crise enfrentada pelo modelo tradicional de produção e consumo caracterizado pelas cadeias longas. No Brasil, trata-se de tema emergente, e, apesar de não existir ainda uma homogeneização
Sthefane Cristina de Lima Duarte +1 more
doaj +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Virtual Teaming in the Agile Supply Chain [PDF]
, 1999 This paper describes the information flows in the supply chain, and identifies knowledge and expertise as richer more capable entities for its management than data or information. It briefly explores how the structure of the automotive supply chain is
Bal, J., Gundry, J., Wilding, Richard D.
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Circular Economy, Industrial Ecology and Short Supply Chain
, 2016 In contrast to the linear “take-make-dispose” model of resource consumption, a new industrial model is proposed in the form of a circular economy. This model aims to optimize the use of resources and to reduce or eliminate waste, and is based on re-use, repair, ecodesign, industrial ecology, sustainable supply and responsible consumption.Industrial ...
Gallaud, Delphine, Laperche, Blandine
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Corporate responsibility, supply chain partnership and performance: An empirical examination [PDF]
, 2012 This is the post-print version of the final paper published in International Journal of Production Economics. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections,
Ghobadian, A +11 more
core +1 more source
The Importance of Supplier Evaluation in Short Supply Chains [PDF]
Studia Universitatis Babes-Bolyai Oeconomica, 2019 Abstract The consideration of supply chains can foster the viability and maintainability of local producers. The formation and retention of the market may be complicated for local producers; therefore it is advisable to take the creation of supply chains into consideration.
Gáborné Szűcs Beáta Pató +1 more
openaire +1 more source