Results 131 to 140 of about 2,463,737 (363)

Cycle-skipping strategy with intake air cut off for natural gas fueled Si engine. [PDF]

Sci Prog, 2021
Tunçer E, Sandalci T, Pusat S, Balcı Ö, Karagöz Y.   +4 more
europepmc   +1 more source

Experimental studies of CAI combustion in a four-stroke GDI engine with an air-assisted injector

, 2007
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.CAI combustion and the factors affecting it were intensively investigated in a single cylinder, air-assisted gasoline direct injection engine.
Brouzos, Nikolaos P
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Variation of Engine Performance and Emissions using Ethanol Blends.

The limited fossil fuel resources along with the increased public concerns about pollution levels have increased the need for alternative fuels for use in internal combustion engines.
Abuhabaya, Abdullah, Fieldhouse, John D.
core  

Study of fuel injection and mixture formation for a gasoline direct injection engine

, 2005
Future requirements for lower automotive emissions have lead to the development of new internal combustion (IC) engine technologies. Gasoline Direct Injection (GDI), for example, is one of these promising new IC engine concepts.
Reveille, T.
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

CFD Simulation of Pre-Chamber Spark-Ignition Large Bore CNG Engine: Model Development, Practical Applications, and Experimental Validation

Energies
This study develops and validates a three-dimensional CFD model for a 12 L large-bore active-type pre-chamber spark-ignition (PCSI) engine fueled by natural gas.
Soo-Jin Jeong, Seokpan Seo, Seong-Joon Moon   +2 more
doaj   +1 more source

Evolution of lubricant degradation and lubricant behaviour in a piston assembly of a reciprocating gasoline engine [PDF]

, 2013
The most difficult and challenging area for the tribology of reciprocating internal combustion engines to improve efficiency and life is the lubricant health within the piston ring pack.
Notay, Rai Bahadur Raman Singh
core