Results 261 to 270 of about 6,019,441 (302)
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Glycobiology, 1991
Cytidine 5'-monophosphosialic acid (CMP-sialic acid) is the activated form of sialic acid which is required for the biosynthesis of sialic acid-containing complex carbohydrates. Its discovery over 30 years ago by the laboratory of Dr Saul Roseman was a landmark in research dealing with the biosynthesis of these compounds.
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Cytidine 5'-monophosphosialic acid (CMP-sialic acid) is the activated form of sialic acid which is required for the biosynthesis of sialic acid-containing complex carbohydrates. Its discovery over 30 years ago by the laboratory of Dr Saul Roseman was a landmark in research dealing with the biosynthesis of these compounds.
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Turnover of Free Sialic Acid, CMP‐Sialic Acid, and Bound Sialic Acid In Rat Brain
Journal of Neurochemistry, 1981Abstract: Adult male rats were injected intraventricularly with N‐[3H]acetylmannosamine. After different time intervals the rats were killed and free sialic acid, CMP‐sialic acid, lipid‐ and protein‐bound sialic acid were isolated from brain and the specific radioactivities determined. Maximal specific radioactivity was reached after approximately 4 h
W, Ferwerda, C M, Blok, J, Heijlman
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Effective Assignment of α2,3/α2,6-Sialic Acid Isomers by LC-MS/MS-Based Glycoproteomics.
Angewandte Chemie, 2018Distinct structural changes of the α2,3/α2,6-sialic acid glycosidic linkages on glycoproteins are of importance in cancer biology, inflammatory diseases, and virus tropism.
Christian Pett +9 more
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Experientia, 1990
The literature contains several reviews on lectins in general, covering mainly those from plants and invertebrates. However, the sialic acid binding lectins have not been reviewed so far. Considering the importance of sialic acids in cell sociology, lectins which specifically recognize terminal sialic acid residues are potentially useful as analytical ...
C, Mandal, C, Mandal
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The literature contains several reviews on lectins in general, covering mainly those from plants and invertebrates. However, the sialic acid binding lectins have not been reviewed so far. Considering the importance of sialic acids in cell sociology, lectins which specifically recognize terminal sialic acid residues are potentially useful as analytical ...
C, Mandal, C, Mandal
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2014
Sialic acids are nine-carbon acidic monosaccharides found in terminal position of glycan chains. The sialylation of cell surface glycoconjugates is frequently altered in cancers, resulting in the expression of sialylated tumor-associated carbohydrate antigens that are specific markers for this disease.
Delannoy, Philippe, Julien, Sylvain
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Sialic acids are nine-carbon acidic monosaccharides found in terminal position of glycan chains. The sialylation of cell surface glycoconjugates is frequently altered in cancers, resulting in the expression of sialylated tumor-associated carbohydrate antigens that are specific markers for this disease.
Delannoy, Philippe, Julien, Sylvain
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Nonulosaminic Acid (Sialic Acid) in Protists
Nature, 1960NONULOSAMINIC ACID1, a group of simple and substituted 9-carbon sugars containing nitrogen, was thought restricted to mammals until it was found in the supernates of Escherichia coli and Citrobacter freundii cultures, but not in the supernates of Salmonella, Shigella, Pneumococcus or Bacillus cultures2.
S, AARONSON, T, LESSIE
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Synthesis of sialic acid-containing nucleotide sugars: CMP-sialic acid analogs
Carbohydrate Research, 1992Syntheses of some sialic acid-containing nucleotide sugars are reported. The reaction of methyl[(2-hydroxy)ethyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto -2- nonulopyranosid]onate (4) with various fully protected hydrogen phosphonates of nucleotides (5a-c) in the presence of 2,4,6-triisopropylbenzenesulfonyl chloride ...
K, Ikeda, Y, Nagao, K, Achiwa
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2019
Sialic acid (Sia) is involved in many biological activities and commonly occurs as a monosialyl residue at the nonreducing terminal end of glycoconjugates. The loss of activity of UDP-GlcNAc2-epimerase/ManNAc kinase, which is a key enzyme in Sia biosynthesis, is lethal to the embryo, which clearly indicates the importance of Sia in embryogenesis ...
Chihiro, Sato, Ken, Kitajima
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Sialic acid (Sia) is involved in many biological activities and commonly occurs as a monosialyl residue at the nonreducing terminal end of glycoconjugates. The loss of activity of UDP-GlcNAc2-epimerase/ManNAc kinase, which is a key enzyme in Sia biosynthesis, is lethal to the embryo, which clearly indicates the importance of Sia in embryogenesis ...
Chihiro, Sato, Ken, Kitajima
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