Results 121 to 130 of about 70,942 (317)
Combinatorial Design of a Sialic Acid-Imprinted Binding Site [PDF]
Liliia Mavliutova +3 more
openalex +1 more source
Enzymatic Removal of Sialic Acid from Human Factor IX and Factor X Has No Effect on Their Coagulant Activity [PDF]
Dwaipayan Bharadwaj +3 more
openalex +1 more source
Objective The transition from asymptomatic antinuclear antibody (ANA) positivity to systemic autoimmune rheumatic disease (SARD) is associated with increased production of proinflammatory factors such as tumor necrosis factor α (TNFα). Here we investigate whether the relative absence of inflammation in asymptomatic ANA+ individuals (ANA+NS) results ...
Carolina Muñoz‐Grajales +8 more
wiley +1 more source
Cloning of hemagglutinin (HA) protein of influenza A virus - Potential for sialic acid linkage discrimination [PDF]
The initial step in infection of a cell by influenza A virus is the attachment of a virus particle to the target cell. This is accomplished by interaction of a glycoprotein, hemagglutinin (HA), found on the surface of the viral lipid membrane with cell ...
O'Connor, Brendan, Szczepaniak, Jakub
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Sialic Acid Content And The Biological Activity Of Stuart Factor (F X) [PDF]
Alfred M. Engel
openalex +1 more source
Absolute bioavailability and intravenous pharmacokinetics of N‐acetyl‐D‐mannosamine in humans
Aims N‐acetyl‐D‐mannosamine monohydrate (ManNAc) is a naturally occurring monosaccharide that has attracted considerable attention for its potential in treating GNE myopathy, a rare autosomal recessive muscle disorder. Despite its promise as an oral treatment, the absolute bioavailability of oral ManNAc has not been determined and there has been no ...
Tahlia R. Meola +6 more
wiley +1 more source
Dynamic pH profiles drive higher cell‐specific and volumetric productivity
Implementation of dyamic pH profiles for increased CHO cell culture productivity. Abstract Mammalian cell cultures in bioreactors rely heavily on critical process parameter control to ensure optimal growth, productivity, and reproducibility to produce recombinant therapeutic proteins. Culture pH has been shown to be a critical parameter that influences
Stephanie R. Klaubert +6 more
wiley +1 more source
Inducible protein expression is a cornerstone of many aspects of industrial and molecular biotechnological processes. 2′‐fucosyl isopropyl‐β‐D‐thiogalactopyranose (2′F‐IPTG) and 2′‐fucosyl isobutyl‐C‐galactoside (2′F‐IBCG) mimics were explored for protein expression studies.
Ashley E. DeYong +6 more
wiley +1 more source
A novel family of bacterial sialic acid binding adhesins? [PDF]
of Distinction at Nationwide Children's Annual Research RetreatThird place in Biomedical Sciences at the Denman Undergraduate Research ForumPlatelet binding is a critical step in the development of Infective Endocarditis (IE), an infection of the ...
Patel, Surina
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