Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi+2 more
wiley +1 more source
Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization. [PDF]
Fliniaux I+9 more
europepmc +1 more source
Role of Sialic Acid in Potassium Transport of L1210 Leukaemia Cells [PDF]
J. Leslie Glick, Sherwood Githens
openalex +1 more source
Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
FLUOROMETRIC ASSAY OF SIALIC ACID IN BRAIN GANGLIOSIDES.
Helen H. Hess, Edward Rolde
openalex +2 more sources
Influenza B Virus Receptor Specificity: Closing the Gap between Binding and Tropism
Influenza A and influenza B viruses (FLUAV and FLUBV, respectively) cause significant respiratory disease, hospitalization, and mortality each year. Despite causing at least 25% of the annual disease burden, FLUBV is historically understudied.
Caroline K. Page, Stephen Mark Tompkins
doaj +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu+4 more
wiley +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui+4 more
wiley +1 more source
Clinical and Diagnostic Significance of Sialic Acids Determination in Biological Material. [PDF]
Volkhina IV, Butolin EG.
europepmc +1 more source
Partial characterization of the sialic acid-free forms of α1-acid glycoprotein from human plasma [PDF]
Karl Schmid+4 more
openalex +1 more source