Results 171 to 180 of about 5,067,072 (323)

Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics

Alimentary Pharmacology &Therapeutics, EarlyView.
Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen, Henriette Ytting, Annelaura Bach Nielsen, Mikkel Parsberg Werge, Elias Badal Rashu, Liv Eline Hetland, Mira Thing, Puria Nabilou, Johan Burisch, Anders Ellekær Junker, Lise Hobolth, Christian Mortensen, Flemming Tofteng, Flemming Bendtsen, Søren Møller, Mogens Vyberg, Reza Rafiolsadat Serizawa, Marie Winther‐Sørensen, Jesper Sloth Kellemann, Lise Lotte Gluud, Nicolai Jacob Wewer Albrechtsen   +20 more
wiley   +1 more source

Early in vitro evidence indicates that deacetylated sialic acids modulate multi-drug resistance in colon and lung cancers via breast cancer resistance protein. [PDF]

Front Oncol, 2023
Tuffour I, Amuzu S, Bayoumi H, Surtaj I, Parrish C, Willand-Charnley R.   +5 more
europepmc   +1 more source

Sialic Acid as an Index of the κ-Casein Content of Bovine Skimmilk

, 1963
J.R. Marier, H. Tessier, Dyson Rose
openalex   +1 more source

Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration.

Physiological Reviews, 2014
R. Schnaar, R. Gerardy-Schahn, H. Hildebrandt   +2 more
semanticscholar   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

The SARS-CoV-2 Spike Glycoprotein Directly Binds Exogeneous Sialic Acids: A NMR View. [PDF]

Angew Chem Int Ed Engl, 2022
Unione L, Moure MJ, Lenza MP, Oyenarte I, Ereño-Orbea J, Ardá A, Jiménez-Barbero J.   +6 more
europepmc   +1 more source

A histochemical comparison of the O-acylated sialic acids of the epithelial mucins in ulcerative colitis, Crohn's disease, and normal controls. [PDF]

, 1979
C.F.A. CULLING, P. E. Reid, William L. Dunn   +2 more
openalex   +1 more source

Exploring Siglecs: Potential Modulators of Immune Cells in Food Allergy and Therapeutic Applications

Clinical &Experimental Allergy, EarlyView.
Sialic acid‐binding immunoglobulin‐type lectins (Siglecs) are inhibitory receptors present on all immune cells involved in the allergic reaction. Currently, research is mostly focussed on targeting Siglecs on mast cells to possibly treat food allergies.
J. S. H. Schaapherder, K. C. M. Verhoeckx, A. M. Ehlers, E. F. Knol, A. C. Knulst, L. A. P. M. Meulenbroek   +5 more
wiley   +1 more source

NXPE1 alters the sialoglycome by acetylating sialic acids in the human colon. [PDF]

Nat Commun
Lee BS, Cook A, Sur S, Dobbyn L, Popoli M, Khalili S, Zhou S, Bettegowda C, Papadopoulos N, Gabrielson K, Buckhaults P, Vogelstein B, Kinzler KW, Wyhs N.   +13 more
europepmc   +1 more source