Results 151 to 160 of about 70,786 (313)

Clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, EarlyView.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala   +14 more
wiley   +1 more source

The Sialic Acids

Journal of Biological Chemistry, 1973
Don M. Carlson, Edward J. McGuire, George W. Jourdian, Saul Roseman   +3 more
  +4 more sources

The Sialic Acids

Journal of Biological Chemistry, 1971
George W. Jourdian, Lawrence Dean, Saul Roseman   +2 more
openaire   +2 more sources

Cell Membrane Sialome: Sialic Acids as Therapeutic Targets and Regulators of Drug Resistance in Human Cancer Management. [PDF]

Cancers (Basel), 2023
Jastrząb P, Narejko K, Car H, Wielgat P.   +3 more
europepmc   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization. [PDF]

Front Cell Dev Biol, 2022
Fliniaux I, Marchand G, Molinaro C, Decloquement M, Martoriati A, Marin M, Bodart JF, Harduin-Lepers A, Cailliau K, Cailliau K.   +9 more
europepmc   +1 more source

Lack of Lumpfish (Cyclopterus lumpus) Susceptibility to the Infectious Salmon Anaemia Virus (ISAV) Using In Vivo Challenges

Journal of Fish Diseases, EarlyView.
ABSTRACT Infectious salmon anaemia virus (ISAV) can cause disease and mortality in Atlantic salmon (Salmo salar). The virus is endemic in several regions including the Atlantic coast of Canada. Lumpfish (Cyclopterus lumpus) are increasingly utilised as cleaner fish to control sea lice levels in Atlantic salmon farms.
Nellie Gagné, Delphine Ditlecadet, Kristine Hébert, Chantal Audet, Steven Leadbeater, Andrew K. Swanson   +5 more
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Clinical and Diagnostic Significance of Sialic Acids Determination in Biological Material. [PDF]

Biochem Mosc Suppl B Biomed Chem, 2022
Volkhina IV, Butolin EG.
europepmc   +1 more source