Results 151 to 160 of about 863,961 (270)
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
ATP1B2 and GLAST identify two astrocyte subpopulations in the hippocampus with distinct molecular signatures. Transcriptomic shifts during aging differ between both subpopulations. Aged ATP1B2+ astrocytes rewire their metabolism while double‐positive aged astrocytes display a reduced synaptogenic capability.
Lucía Casares‐Crespo +6 more
wiley +1 more source
Intracellular Delivery of Hydrophilic Glycans Using Superchaotropic Clusters
Superchaotropic boron clusters are demonstrated to deliver hydrophilic glycans directly into mammalian cells, removing the need for acetylation and cytotoxic solvents such as DMSO. Azido glycans for metabolic oligosaccharide engineering, and trehalose, were delivered and the successful azido‐labelling of glycoproteins, cell surface glycans, and ...
Qiao Tang +2 more
wiley +2 more sources
Gut microbiota associated with pediatric autism spectrum disorder exhibit functional heterogeneity characterized by altered fecal lipopolysaccharide landscapes, metabolic remodeling, and enhanced microglial inflammatory responses despite largely preserved microbial composition.
Stefania De Chiara +10 more
wiley +1 more source
Are sialic acids involved in COVID-19 pathogenesis? [PDF]
Dhar C +7 more
europepmc +1 more source
Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins
Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano +3 more
wiley +1 more source
Clinical and Diagnostic Significance of Sialic Acids Determination in Biological Material. [PDF]
Volkhina IV, Butolin EG.
europepmc +1 more source
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora +12 more
wiley +1 more source

