Results 181 to 190 of about 70,452 (316)

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans. [PDF]

Glycobiology, 2023
Lewis AL, Toukach P, Bolton E, Chen X, Frank M, Lütteke T, Knirel Y, Schoenhofen I, Varki A, Vinogradov E, Woods RJ, Zachara N, Zhang J, Kamerling JP, Neelamegham S, SNFG Discussion Group.   +15 more
europepmc   +1 more source

Effect of Age on Serum-bound Sialic Acid in Rats [PDF]

, 1966
David H. Dail, Jonas E. Richmond
openalex   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Are sialic acids involved in COVID-19 pathogenesis? [PDF]

Glycobiology, 2021
Dhar C, Sasmal A, Diaz S, Verhagen A, Yu H, Li W, Chen X, Varki A.   +7 more
europepmc   +1 more source

The Thiobarbituric Acid Assay of Sialic Acids

Journal of Biological Chemistry, 1959
Publisher Summary This chapter discusses the different aspects of thiobarbituric acid assay of sialic acid. Periodate oxidation of the neuraminic acid backbone of sialic acids results in the formation of β -formylpyruvic acid from carbon atoms 1 to 4.
openaire   +3 more sources

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

SARS-CoV-2 Spike N-Terminal Domain Engages 9-O-Acetylated α2-8-Linked Sialic Acids. [PDF]

ACS Chem Biol, 2023
Tomris I, Unione L, Nguyen L, Zaree P, Bouwman KM, Liu L, Li Z, Fok JA, Ríos Carrasco M, van der Woude R, Kimpel ALM, Linthorst MW, Kilavuzoglu SE, Verpalen ECJM, Caniels TG, Sanders RW, Heesters BA, Pieters RJ, Jiménez-Barbero J, Klassen JS, Boons GJ, de Vries RP.   +21 more
europepmc   +1 more source

The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans [PDF]

, 2017
Lewis, Amanda L, Lewis, Warren G, Robinson, Lloyd S   +2 more
core   +2 more sources

Four‐gene Prognostic Signature and Risk of Brain Metastasis of Lung Adenocarcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Brain metastasis has a high incidence and poor prognosis in lung adenocarcinoma (LUAD). We sought to identify genes associated with LUAD brain metastasis and with the prognosis of patients with LUAD. Differential gene expression analysis was performed on LUAD patients with and without distant metastasis from the Cancer Genome Atlas (TCGA ...
Zheng Gong, Fengyuan Yu, Chen Li, Bingying Zhao, Miaowei Wen, Shanshan Zhang, Zhezhe Xu, Ailu Wu, Rukun Zang, Yuan Li, Hongwei Li, Yipeng Song   +11 more
wiley   +1 more source