Results 201 to 210 of about 70,942 (317)

Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas

, 2014
Cory D. Rillahan, Matthew S. Macauley, Erik Schwartz, Yuan He, Ryan McBride, Britni M. Arlian, Janani Rangarajan, Valery V. Fokin, James C. Paulson   +8 more
openalex   +2 more sources

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

Single Particle Analysis of H3N2 Influenza Entry Differentiates the Impact of the Sialic Acids (Neu5Ac and Neu5Gc) on Virus Binding and Membrane Fusion. [PDF]

J Virol, 2023
Chien YA, Alford BK, Wasik BR, Weichert WS, Parrish CR, Daniel S.   +5 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

The SARS-CoV-2 Spike Glycoprotein Directly Binds Exogeneous Sialic Acids: A NMR View. [PDF]

Angew Chem Int Ed Engl, 2022
Unione L, Moure MJ, Lenza MP, Oyenarte I, Ereño-Orbea J, Ardá A, Jiménez-Barbero J.   +6 more
europepmc   +1 more source

Use of Butyl Acetate in Determination of Sialic Acid. [PDF]

, 1959
T. A. Miettinen, I.‐T. Takki‐Luukkainen, I. Smith-Kielland, R. Sömme, Einar Stenhagen, H. Palmstierna   +5 more
openalex   +1 more source

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

Plant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij, Myrna J. M. Bunte, Lisa Nijhof, Sanaz Mokhtari, Hein Overmars, Arjen Schots, Ruud H. P. Wilbers, Pieter Nibbering   +7 more
wiley   +1 more source

NXPE1 alters the sialoglycome by acetylating sialic acids in the human colon. [PDF]

Nat Commun
Lee BS, Cook A, Sur S, Dobbyn L, Popoli M, Khalili S, Zhou S, Bettegowda C, Papadopoulos N, Gabrielson K, Buckhaults P, Vogelstein B, Kinzler KW, Wyhs N.   +13 more
europepmc   +1 more source

The role of cell surface sialic acids for SARS-CoV-2 infection. [PDF]

Glycobiology, 2021
Sun XL.
europepmc   +1 more source