Results 231 to 240 of about 69,641 (328)

Genetic Divergence and Antibody Expression Influence the N‐Glycomes of CHO‐K1 and CHO‐S Cells

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 11, Page 3160-3175, November 2025.
ABSTRACT While Chinese hamster ovary (CHO) cells continue to be the workhorse of recombinant therapeutic protein production, decades of genetic divergence in the industrially relevant CHO‐K1 and CHO‐S cell lines, are likely to have resulted in differing glycosylation capabilities. Glycosylation can influence the efficacy, serum half‐life, and safety of
Roberto Donini   +6 more
wiley   +1 more source

Effects of TcFLA‐1BP and TcGP72 Deletion on the Infectivity and Survival of Trypanosoma cruzi in Cell Cultures

open access: yesCell Biology International, Volume 49, Issue 11, Page 1395-1410, November 2025.
ABSTRACT Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected tropical disease with limited treatment options and no available vaccine. Understanding the role of proteins in the parasite's biological cycle is critical for advancing vaccine development and optimizing therapies.
Normanda Souza‐Melo   +2 more
wiley   +1 more source

Early in vitro results indicate that de-O-acetylated sialic acids increase Selectin binding in cancers. [PDF]

open access: yesFront Oncol
Das K   +7 more
europepmc   +1 more source

The Role of Sialic Acids in the Establishment of Infections by Pathogens, With Special Focus on Leishmania. [PDF]

open access: yesFront Cell Infect Microbiol, 2021
Cavalcante T   +4 more
europepmc   +1 more source

Diabetes and Obesity Modify the Effect of Alcohol Consumption on Carbohydrate‐Deficient Transferrin

open access: yesEndocrinology, Diabetes &Metabolism, Volume 8, Issue 6, November 2025.
There is an interaction between alcohol consumption and factors associated with insulin resistance in relation to transferrin sialylation. The sensitivity of carbohydrate‐deficient transferrin for detecting heavy alcohol consumption might be limited in patients with obesity or diabetes.
Tomás González‐Vidal   +7 more
wiley   +1 more source

Sialic acids as attachment factors in mosquitoes mediating Japanese encephalitis virus infection. [PDF]

open access: yesJ Virol
He Y   +17 more
europepmc   +1 more source

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