Results 231 to 240 of about 70,942 (317)

Effect of Sialic Acid on Mammalian Cell Culture and Protein Expression: A Potential Productivity Enhancer for Biopharmaceutical Cell Culture Processes [PDF]

, 2020
Xiangsong Chen, Shang Xiao, Jinyong Wu, Jianming Yao   +3 more
openalex   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

Chemoenzymatically Synthesized O‐Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhiyong Zhang, Ruonan Liang, Kevin C. Hooijschuur, Robert P. de Vries, Zeshi Li, Geert‐Jan Boons   +5 more
wiley   +2 more sources

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

Advanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man, Lin Du, Ying Liu, Zehan Pang, Hongyan Zhu, Bixia Hong, Zhichao Xu, Huahao Fan   +7 more
wiley   +1 more source

Early in vitro results indicate that de-O-acetylated sialic acids increase Selectin binding in cancers. [PDF]

Front Oncol
Das K, Schulte M, Gerhart M, Bayoumi H, Paulson D, Fink DM, Parrish C, Willand-Charnley R.   +7 more
europepmc   +1 more source

The Role of Sialic Acids in the Establishment of Infections by Pathogens, With Special Focus on Leishmania. [PDF]

Front Cell Infect Microbiol, 2021
Cavalcante T, Medeiros MM, Mule SN, Palmisano G, Stolf BS.   +4 more
europepmc   +1 more source

Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth

, 2022
Tiago Bozzola, Mariafrancesca Scalise, Christer Larsson, Michael C. Newton-Vesty, Caterina Rovegno, Ankita Mitra, Jonathan Cramer, Weixiao Yuan Wahlgren, Partha Radhakrishnan Santhakumari, Richard Johnsson, Oliver Schwardt, Beat Ernst, Rosmarie Friemann, Renwick C. J. Dobson, Cesare Indiveri, Jenny Schelin, Ulf J. Nilsson, Ulf Ellervik   +17 more
openalex   +1 more source

Characterizing Spatiotemporal Expansion of Pseudomonas aeruginosa Communities in Polymer and Mucin Gel Environments

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 420-435, February 2026.
ABSTRACT Opportunistic colonization and recurring infection by Pseudomonas aeruginosa are substantial risks to lung functionality for people with underlying respiratory diseases such as cystic fibrosis and chronic obstructive pulmonary disease. The complex metabolic and phenotypic adaptations P.
Morgan S. Kim, Glynis L. Kolling, Katharina Ribbeck, Shayn M. Peirce, Jason A. Papin, Roseanne M. Ford   +5 more
wiley   +1 more source

The Sialic Acids

Journal of Biological Chemistry, 1966
Donald G. Comb, Donald R. Watson, Saul Roseman   +2 more
  +4 more sources

Sialic acids as attachment factors in mosquitoes mediating Japanese encephalitis virus infection. [PDF]

J Virol
He Y, Miao C, Yang S, Xu C, Liu Y, Zhu X, Wen Y, Wu R, Zhao Q, Huang X, Yan Q, Lang Y, Zhao S, Wang Y, Han X, Cao S, Hu Y, Du S.   +17 more
europepmc   +1 more source