Sweet Surprises: Decoding Tumor-Associated Glycosylation in Cancer Progression and Therapeutic Potential. [PDF]
Giurini EF, Pappas SG, Gupta KH.
europepmc +1 more source
Epitope mapping of vaccine antigens Tc24 and TSA1 with antibodies from Trypanosoma cruzi-infected patients. [PDF]
Dumonteil E, Herrera C.
europepmc +1 more source
Variation in surface protein expression leads to heterogeneous Trypanosoma cruzi populations during host cell infection. [PDF]
Cruz-Saavedra L +3 more
europepmc +1 more source
Genetic transformation of <i>Gardnerella</i> species and characterization of vaginolysin and sialidase mutants. [PDF]
Klimowicz AK +3 more
europepmc +1 more source
Vaginal Microecology Disturbance and Immune Dysregulation Are Associated with Human Papillomavirus Infection: Insights from a Two-year Study of Vaginal Microecology. [PDF]
Sheng Q, Cui X, Zhang J, Yang F, Zeng L.
europepmc +1 more source
Diagnostic accuracy of an enzyme-based point-of-care test versus Nugent score for bacterial vaginosis among pregnant women attending routine antenatal care in Zambia. [PDF]
Sorano S +16 more
europepmc +1 more source
Antibody-lectin chimeras for glyco-immune checkpoint blockade. [PDF]
Stark JC +20 more
europepmc +1 more source
The Function of Sialidase Revealed by Sialidase Activity Imaging Probe [PDF]
Sialidase cleaves sialic acid residues from glycans such as glycoproteins and glycolipids. In the brain, desorption of the sialic acid by sialidase is essential for synaptic plasticity, learning and memory and synaptic transmission. BTP3-Neu5Ac has been developed for sensitive imaging of sialidase enzyme activity in mammalian tissues.
Akira Minami +2 more
exaly +3 more sources
A Sialidase Mutant Displaying trans-Sialidase Activity
Trypanosoma cruzi, the agent of Chagas disease, expresses a modified sialidase, the trans-sialidase, which transfers sialic acid from host glycoconjugates to beta-galactose present in parasite mucins. Another American trypanosome, Trypanosoma rangeli, expresses a homologous protein that has sialidase activity but is devoid of transglycosidase activity.
Gaston Paris +2 more
exaly +5 more sources
Trypanosoma rangeli sialidase lacks trans-sialidase activity [PDF]
Extracts and tissue culture supernatants of axenic forms of T. rangeli were assayed for the presence of sialidase and trans-sialidase activities. Using sialyl(alpha 2-3)lactose, sialyl(alpha 2-6)lactose, poly(alpha 2-8)N-acetylneuraminic acid, fetuin and 4-methylumbelliferyl-N-acetylneuraminic acid as sialic acid donors, and lactose as a sialic acid ...
Stephen Tomlinson, V Nussenzweig
exaly +3 more sources

