Results 271 to 280 of about 10,746,438 (360)

Transcriptomic Responses of the Marine Diatom Phaeodactylum tricornutum to High Carbon and Low Nitrogen Stress

Ecology and Evolution, Volume 16, Issue 1, January 2026.
To elucidate the integrated transcriptional mechanisms underlying diatom acclimation to coupled carbon–nitrogen (CN) imbalance, we employed RNA sequencing (RNA‐Seq) to characterize the global transcriptional response of the model diatom Phaeodactylum tricornutum to high CO2 (~2000 μatm) and low nitrogen (10% of nitrogen concentration in f/2 medium ...
Yi Zhang, Jiawen Duan, Yimeng Zheng, Xiaoqi Chen, Chenhui Li, Zhenyu Xie, Aiyou Huang   +6 more
wiley   +1 more source

Costs of Treating Uncomplicated Sickle Cell Complications in a Day Hospital Setting in Equatorial Africa. [PDF]

Anemia
Ngolet LO, Taylor J, de Chabervy Atipo A, Mikia CP, Bango C, Bantsimba FS, Ondzotto Ibatta I, Dokekias AE.   +7 more
europepmc   +1 more source

MeMAGEN: A Phase IIa/IIb open‐label trial of memantine testing safety and tolerability in sickle cell patients

HemaSphere, Volume 10, Issue 1, January 2026.
ABSTRACT Administration of memantine, an antagonist of the N‐methyl‐ d‐aspartate receptor, prevents Ca2+ overload and dehydration of red blood cells (RBCs) in patients with sickle cell disease (SCD). The objectives of the 1‐year dose‐escalation Phase IIa/IIb Memantine trial (MeMAGEN – NCT 03247218) with 17 SCD patients who were under stable ...
Ariel Koren, Carina Levin, Leonid Livshits, Fabio Valeri, Sari Peretz, Sivan Raz, Anna Yu Bogdanova, Max Gassmann   +7 more
wiley   +1 more source

The impact of social vulnerability on primary vaccine coverage in children with sickle cell disease. [PDF]

Front Public Health
Shi JS, LaFon E, Sutaria A, Attell BK, Zhou M, Tang A, Snyder AB.   +6 more
europepmc   +1 more source

Hypomorphic ATP11c is a novel regulator of decreased efficacy of transfused red blood cells in humans and mice

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Chronic red blood cell (RBC) transfusion sustains patients with diverse hematologic disorders, but repeated transfusion leads to iron overload and alloimmunization. Reducing transfusion burden requires identifying donor units that circulate more effectively after storage, yet determinants of this variability remain incompletely defined.
James C. Zimring, Ariel M. Hay, Monika Dzieciatkowska, Daniel Stephenson, Zachary B. Haiman, Steven Kleinman, Philip J. Norris, Michael P. Busch, Nareg Roubinian, Elisa Fermo, Paola Bianchi, Gregory R. Keele, Grier P. Page, Angelo D'Alessandro   +13 more
wiley   +1 more source

Cohort Tracking of Sickle Cell Trait-Positive Births Identified by Newborn Screening, California, 1991-2013: Public Health Surveillance for Sickle Cell Trait. [PDF]

Public Health Rep
Paulukonis ST, Horiuchi S, Austin T, Vichinsky EP.   +3 more
europepmc   +1 more source

Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Erythropoiesis is a finely regulated process ensuring continuous red blood cell production to maintain oxygen delivery. Disruptions in this process give rise to defective erythropoiesis, characterized by impaired lineage commitment and progenitor development, and ineffective erythropoiesis (IE), marked by expansion of erythroid progenitors ...
Sara El Hoss, Maria A. Lizarralde‐Iragorri, Thiago Trovati Maciel, Olivier Hermine   +3 more
wiley   +1 more source

Electrophysiological and Psychological Correlates of Cognition in Adult Homozygous Sickle Cell Disease Patients. [PDF]

Ann Neurosci
Sahu T, Sinha M, Sinha R, Wasnik P, Ingle A, Tikka SK.   +5 more
europepmc   +1 more source

Knowledge, Attitudes, Practices, and Misconceptions Regarding Vitamins in Blood Metabolism and Anemia Among University Students: A One Center Cross‐Sectional Study in Ghana

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background In Sub‐Saharan Africa, anemia is a significant public health issue, affecting individuals of all ages. While prevention efforts focus on infants, children, and pregnant women, adolescents are overlooked often, leading to ongoing challenges.
David Mawutor Donkor, Gideon Owusu, Victoria Essuon‐Sepah, Obed Asamoah, Isabella Anokye, Alfred Kwadwo Sah, Safianu Apalebilah, Patrick Adu, Joseph Boachie   +8 more
wiley   +1 more source

Impact of sickle cell anaemia on reproductive health: a narrative review. [PDF]

Reprod Health
Kotam GP, Morrison DB, Karikari JN, Mawunyo AO, Kotam J, Osei GN, Adu P.   +6 more
europepmc   +1 more source