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Self-resolution of spontaneous epidural hematoma in sickle cell anemia: A case report [PDF]

Radiology Case Reports
Spontaneous epidural hematoma is a rare and dangerous complication of sickle cell anemia which typically requires surgical management. We present a rare case of a patient with sickle cell anemia and intracranial spontaneous epidural hematoma which ...
Shruti Kumari, MD, Grayson H. Hooper, DO, Ameya Nayate, MD   +2 more
doaj   +2 more sources

Radiologic Evaluation of Paranasal Sinuses in Sickle Cell Anemia and Thalassemia: Case–Control Study [PDF]

Laryngoscope Investigative Otolaryngology
Background Sickle cell disease and thalassemia are inherited hematological disorders that are common worldwide. These patients suffer from chronic hemolytic anemia, which can result in bone marrow dysfunction and, in rare cases, extramedullary ...
Maha A. Alharbi, Ayat AlDarwish, Reem M. Alamier, Nawal E. Omer, Mahmoud A. Alabbad, Abdulmohsin M. Aljassem, Qasem M. ALalwan, Danah H. Althomaly, Hussain Abdullali Albaharna   +8 more
doaj   +2 more sources

Sickle Cell Anemia [PDF]

RadioGraphics, 2001
Sickle cell anemia (SCA) is a disease caused by production of abnormal hemoglobin, which binds with other abnormal hemoglobin molecules within the red blood cell to cause rigid deformation of the cell. This deformation impairs the ability of the cell to pass through small vascular channels; sludging and congestion of vascular beds may result, followed ...
G J, Lonergan, D B, Cline, S L, Abbondanzo   +2 more
  +5 more sources

Role of sickling crisis with serum zinc in children with sickle cell anemia

Advanced Medical Journal, 2022
Background and objectives: Sickle cell anemia causes painful crises by the occlusion of small blood vessels by spontaneous intravascular sickling. The aim of this study is to determine the possible association of Zinc deficiency with painful crises ...
Bahzad Khalid Sharaf, Akrem Mohammad Atrushi   +1 more
doaj   +1 more source

Knowledge and DdeI Based Confirmation of Sickle Cell Anemia Among the Tharu Community

Journal of Nepal Health Research Council, 2022
Background: Sickle cell anemia is an inherited blood disorder caused due to a point mutation at the sixth codon of the ?-globin gene of both alleles. Sickle cell traits occur when the mutation is in one of the two alleles of the ?-globin genes.
Sajani Ghaju, Karan Khadayat, Raju Shrestha, Salan Ghaju, Trishna Manandhar, Bishnu P. Marasini   +5 more
doaj   +1 more source

Treating sickle cell anemia [PDF]

Science, 2020
New drugs, stem cell transplants, and gene therapy show promise in treating sickle cell ...
John F, Tisdale, Swee Lay, Thein, William A, Eaton   +2 more
openaire   +2 more sources

Splenic sequestration and infarction upon exposure to high altitude in adult patients with sickle cell anemia

Journal of Applied Hematology, 2023
Adult patients with sickle cell disease usually have atrophied spleens due to autosplenectomy, and only rarely have complications related to the spleen, such as splenic sequestration and infarctions.
Husain Alkhaldy, Mortadah Alsalman, Mariyyah Almuhaini, Renad Alshehri, Samar Almusaad, Wejdan Al-Qahtani, Tamer A Samih, Mohammed Makkawi   +7 more
doaj   +1 more source

HEMATOPOIETIC STEM CELL TRANSPLANTATION IN THALASSEMIA AND SICKLE CELL DISEASE: EXPERIENCE OF MEDITERRANEAN INSTITUTE OF HEMATOLOGY IN A MULTI-ETHNIC POPULATION.

Mediterranean Journal of Hematology and Infectious Diseases, 2009
Hematopoietic stem cell transplantation (HSCT) still remains the only definitive cure currently available for patients with thalassemia and sickle cell anemia.
Marco Marziali, Antonella Isgrò, Javid Gaziev, Guido Lucarelli   +3 more
doaj   +1 more source

Peripheral Red Blood Cell Split Chimerism as a Consequence of Intramedullary Selective Apoptosis of Recipient Red Blood Cells in a Case of Sickle Cell Disease

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Allogeneic cellular gene therapy through hematopoietic stem cell transplantation is the only radical cure for congenital hemoglobinopathies like thalassemia and sickle cell anemia.
Marco Marziali, Antonella Isgrò, Pietro Sodani, Javid Gaziev, Daniela Fraboni, Katia Paciaroni, Cristiano Gallucci, Cecilia Alfieri, Andrea Roveda, Gioia De Angelis, Luisa Cardarelli, Michela Ribersani, Marco Andreani, Guido Lucarelli   +13 more
doaj   +1 more source

Murine models of sickle cell disease and beta‐thalassemia demonstrate pulmonary hypertension with distinctive features

Pulmonary Circulation, 2021
Sickle cell anemia and β‐thalassemia intermedia are very different genetically determined hemoglobinopathies predisposing to pulmonary hypertension. The etiologies responsible for the associated development of pulmonary hypertension in both diseases are ...
Paul W. Buehler, Delaney Swindle, David I. Pak, Mehdi A. Fini, Kathryn Hassell, Rachelle Nuss, Rebecca B. Wilkerson, Angelo D’Alessandro, David C. Irwin   +8 more
doaj   +1 more source