Results 11 to 20 of about 78,171 (294)

Mortality in children, adolescents and adults with sickle cell anemia in Rio de Janeiro, Brazil [PDF]

open access: hybrid, 2017
OBJECTIVE: To determine the mortality rate of children, adolescents and adults with sickle cell anemia in Rio de Janeiro, Brazil. METHODS: The number of deaths, the mortality rate and the causes of deaths in patients with sickle cell anemia who were ...
Clarisse Lopes de Castro Lobo   +5 more
openalex   +4 more sources

The Virginia Sickle Cell Anemia Awareness Program: Education, Screening, and Counseling [PDF]

open access: green, 1977
In 1968, a program of screening for sickle trait carriers was begun as part of the work of the Hematology Division, Department of Medicine, at the Medical College of Virginia.
Florence N. Cooper, Robert B. Scott
openalex   +3 more sources

Primary stroke in a woman with sickle cell anemia responsive to hydroxyurea therapy. [PDF]

open access: yes, 2014
The most common cause of stroke in children with sickle cell anemia is infarction due to ischemia. In adults, however, stroke is most commonly hemorrhagic in nature. Other causes of stroke in patients with sickle cell disease are very rare. In this short
Ballas, Samir K.   +2 more
core   +2 more sources

Haploidentical HSCT for hemoglobinopathies: improved outcomes with TCRαβ+/CD19+-depleted grafts

open access: yesBlood Advances, 2018
: We examined outcomes of haploidentical hematopoietic cell transplantation (haplo-HCT) using T-cell receptor αβ+ (TCRαβ+)/CD19+-depleted grafts (TCR group, 14 patients) in children with hemoglobinopathies.
Javid Gaziev   +11 more
doaj   +1 more source

The Fabulous Impact of CRISPR Method in Sickle Cell Disease Treatment

open access: yesTrends in Peptide and Protein Sciences, 2021
Sickle cell diseases are the most prevalent monogenic blood diseases with complications such as severe end-organ harm, pain, and reduced life expectancy. Dealing options for sickle cell diseases are inadequate, as there are just two FDA-approved drugs to
Vida Ebrahimi, Atieh Hashemi
doaj   +1 more source

Comorbidities in aging patients with sickle cell disease. [PDF]

open access: yes, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

Hematologic and hemorheological determinants of resting and exercise-induced hemoglobin oxygen desaturation in children with sickle cell disease

open access: yesHaematologica, 2013
The aim of the study was to determine the factors associated with resting and exercise-induced hemoglobin oxygen desaturation. The well-established six-minute walk test was conducted in 107 sickle cell children (50 with sickle hemoglobin C disease and 57
Xavier Waltz   +12 more
doaj   +1 more source

Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania

open access: yesHaematologica, 2011
Background Reduced growth is common in children with sickle cell anemia, but few data exist on associations with long-term clinical course. Our objective was to determine the prevalence of malnutrition at enrolment into a hospital-based cohort and ...
Sharon E. Cox   +8 more
doaj   +1 more source

Sickle Cell Anemia [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1922
Recent medical literature contains the records of three patients, all negroes, or negroes with an admixture of Caucasian blood, in whom severe anemia, characterized by certain peculiar morphologic alterations of the red blood cells, was present. The first case was reported by Herrick.1Washburn2published the records of a patient whose blood showed ...
openaire   +1 more source

Association between sickle cell and β-thalassemia genes and hemoglobin concentration and anemia in children and non-pregnant women in Sierra Leone: ancillary analysis of data from Sierra Leone’s 2013 National Micronutrient Survey

open access: yesBMC Research Notes, 2018
Objective By measuring the associations between the presence of sickle cell and β-thalassemia genes, we assessed the extent to which these hemoglobinopathies contribute to the high prevalence of anemia observed in preschool-aged children and women of ...
James P. Wirth   +4 more
doaj   +1 more source

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