Results 21 to 30 of about 247,564 (312)

Murine models of sickle cell disease and beta‐thalassemia demonstrate pulmonary hypertension with distinctive features

open access: yesPulmonary Circulation, 2021
Sickle cell anemia and β‐thalassemia intermedia are very different genetically determined hemoglobinopathies predisposing to pulmonary hypertension. The etiologies responsible for the associated development of pulmonary hypertension in both diseases are ...
Paul W. Buehler   +8 more
doaj   +1 more source

Mortality in children, adolescents and adults with sickle cell anemia in Rio de Janeiro, Brazil. [PDF]

open access: yes, 2018
OBJECTIVE: To determine the mortality rate of children, adolescents and adults with sickle cell anemia in Rio de Janeiro, Brazil. METHODS: The number of deaths, the mortality rate and the causes of deaths in patients with sickle cell anemia who were ...
Ballas, Samir K.   +5 more
core   +3 more sources

Primary stroke in a woman with sickle cell anemia responsive to hydroxyurea therapy. [PDF]

open access: yes, 2014
The most common cause of stroke in children with sickle cell anemia is infarction due to ischemia. In adults, however, stroke is most commonly hemorrhagic in nature. Other causes of stroke in patients with sickle cell disease are very rare. In this short
Ballas, Samir K.   +2 more
core   +2 more sources

Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Curaçao: Two Case Reports [PDF]

open access: yes, 2013
Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Curaçao: Two Case ...
ACE Andrianarisoa   +17 more
core   +5 more sources

Successful orthotopic liver transplantation in an adult patient with sickle cell disease and review of the literature [PDF]

open access: yes, 2013
Sickle cell disease can lead to hepatic complications ranging from acute hepatic crises to chronic liver disease including intrahepatic cholestasis, and iron overload.
Blinder, Morey A.   +7 more
core   +2 more sources

Sickle Cell Anemia [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1922
Recent medical literature contains the records of three patients, all negroes, or negroes with an admixture of Caucasian blood, in whom severe anemia, characterized by certain peculiar morphologic alterations of the red blood cells, was present. The first case was reported by Herrick.1Washburn2published the records of a patient whose blood showed ...
openaire   +2 more sources

Hydroxyurea for Children with Sickle Cell Anemia in Sub‐Saharan Africa

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Hydroxyurea is an effective treatment for sickle cell anemia, but few studies have been conducted in sub‐Saharan Africa, where the burden is greatest.
L. Tshilolo   +10 more
semanticscholar   +1 more source

Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania

open access: yesHaematologica, 2011
Background Reduced growth is common in children with sickle cell anemia, but few data exist on associations with long-term clinical course. Our objective was to determine the prevalence of malnutrition at enrolment into a hospital-based cohort and ...
Sharon E. Cox   +8 more
doaj   +1 more source

Hematologic and hemorheological determinants of resting and exercise-induced hemoglobin oxygen desaturation in children with sickle cell disease

open access: yesHaematologica, 2013
The aim of the study was to determine the factors associated with resting and exercise-induced hemoglobin oxygen desaturation. The well-established six-minute walk test was conducted in 107 sickle cell children (50 with sickle hemoglobin C disease and 57
Xavier Waltz   +12 more
doaj   +1 more source

Prevalence of sickle cell disease and sickle cell trait in national neonatal screening studies

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2011
Sickle cell anemia is the best known hereditary blood disorder; there are serious complications associated with the condition. Diagnosis and early intervention reduce morbidity and mortality.
Luciana Garcia Lervolino   +5 more
doaj   +1 more source

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