Saudi SCD patients’ symptoms and quality of life relative to the number of ED visits [PDF]
Background Individuals living with sickle cell disease (SCD) have significantly increased emergency department (ED) use compared to the general population. In Saudi Arabia, health care is free for all individuals and therefore has no bearing on increased
Ahmed, Anwar E. +6 more
core +2 more sources
Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S. +8 more
core +2 more sources
Prevalence of sickle cell disease and sickle cell trait in national neonatal screening studies
Sickle cell anemia is the best known hereditary blood disorder; there are serious complications associated with the condition. Diagnosis and early intervention reduce morbidity and mortality.
Luciana Garcia Lervolino +5 more
doaj +1 more source
Treatment of severe malaria with artemisinin derivatives in patients with comorbid conditions such as sickle cell anemia must be considered with precaution.
Abdulrahman Hummadi +3 more
doaj +1 more source
In this study, we employed a Bayesian network approach for the classification of sickle cell anemia in teenagers based on their medical data. Sickle cell anemia is a hereditary blood disorder characterized by the presence of abnormal hemoglobin, leading ...
Blessing Ekong +4 more
doaj +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST +5 more
core +1 more source
Background Recent evidence suggests that red blood cell aggregation and the ratio of hematocrit to blood viscosity (HVR), an index of the oxygen transport potential of blood, might considerably modulate blood flow dynamics in the microcirculation.
Julien Tripette +10 more
doaj +1 more source
Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia [PDF]
Retrospective studies suggest that there is high mortality in children with sickle cell anemia (SCA) and severe malaria. We assessed mortality in Ugandan children with severe malarial anemia (SMA, n = 232) or cerebral malaria (CM, n = 267) by sickle cell
Bangirana, Paul +5 more
core +1 more source
Albuminuria Predicts a Rapid Decline in Kidney Function in 2 International, Longitudinal Cohorts of Adults With Sickle Cell Anemia. [PDF]
ABSTRACT Chronic kidney disease (CKD) is common and a major contributor to increased morbidity and early mortality in people with sickle cell anemia (SCA). Urine albumin‐to‐creatinine ratio (uACR) is recommended to identify patients with SCA‐related CKD but its utility in predicting long‐term kidney dysfunction remains unclear in this patient ...
Bartolucci P +12 more
europepmc +2 more sources

