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Sickle cell anemia

Nursing Made Incredibly Easy!, 2019
Sickle cell anemia is the most severe form of sickle cell disease and is the homozygous state for hemoglobin S. Sickle cell anemia is prevalent in Africa, the Middle East, and parts of India. It is common in geographical areas where malaria is widespread.
Esther Bassaw
semanticscholar   +1 more source

Red blood cell aggregation, aggregate strength and oxygen transport potential of blood are abnormal in both homozygous sickle cell anemia and sickle-hemoglobin C disease

Haematologica, 2009
Background Recent evidence suggests that red blood cell aggregation and the ratio of hematocrit to blood viscosity (HVR), an index of the oxygen transport potential of blood, might considerably modulate blood flow dynamics in the microcirculation.
Julien Tripette, Tamas Alexy, Marie-Dominique Hardy-Dessources, Daniele Mougenel, Eric Beltan, Tawfik Chalabi, Roger Chout, Maryse Etienne-Julan, Olivier Hue, Herbert J. Meiselman, Philippe Connes   +10 more
doaj   +1 more source

Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography.

New England Journal of Medicine, 1998
BACKGROUND Blood transfusions prevent recurrent stroke in children with sickle cell anemia, but the value of transfusions in preventing a first stroke is unknown.
R. Adams, V. Mckie, L. Hsu, B. Files, E. Vichinsky, C. Pegelow, M. Abboud, D. Gallagher, A. Kutlar, F. Nichols, D. Bonds, D. Brambilla, G. Woods, N. Olivieri, C. Driscoll, Scott T. Miller, Winfred C. Wang, Anne Hurlett, C. Scher, B. Berman, Elizabeth Carl, Anne M. Jones, E. Roach, Elizabeth C. Wright, R. Zimmerman, M. Waclawiw   +25 more
semanticscholar   +1 more source

Pneumococcal vaccination coverage among children with sickle cell anemia, sickle cell trait, and normal hemoglobin [PDF]

, 2018
BackgroundChildren with sickle cell anemia and sickle cell trait are at an increased risk of invasive pneumococcal disease compared to children with normal hemoglobin.
Dombkowski, Kevin J., Gondhi, Jennifer P., Jary, Hannah K., Kleyn, Mary, Reeves, Sarah L., Wagner, Abram L.   +5 more
core   +1 more source

Prevalence of Haemoglobine s in Araraquara-SP Population.

Revista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal, 2015
The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle ...
Bruno Rocha de Jesus, Heloise Brait Rin, Elza Regina Manzolli Leite, Amauri Antiquera Leite, Miriane da Costa Gileno   +4 more
doaj   +1 more source

A New Strategy for the Morphological and Colorimetric Recognition of Erythrocytes for the Diagnosis of Forms of Anemia based on Microscopic Color Images of Blood Smears [PDF]

International journal of advanced computer science and applications (IJACSA), 2020, 11 (7), pp.488-497, 2023
The detection of red blood cells based on morphology and colorimetric appearance is very important in improving hematology diagnostics. There are automatons capable of detecting certain forms, but these have limitations with regard to the formal identification of red blood cells because they consider certain cells to be red blood cells when they are ...
arxiv  

Fourier Transform of Percoll Gradients Boosts CNN Classification of Hereditary Hemolytic Anemias [PDF]

arXiv, 2021
Hereditary hemolytic anemias are genetic disorders that affect the shape and density of red blood cells. Genetic tests currently used to diagnose such anemias are expensive and unavailable in the majority of clinical labs. Here, we propose a method for identifying hereditary hemolytic anemias based on a standard biochemistry method, called Percoll ...
arxiv  

Comorbidities in aging patients with sickle cell disease. [PDF]

, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

Hemorheological risk factors of acute chest syndrome and painful vaso-occlusive crisis in children with sickle cell disease

Haematologica, 2012
Background Little is known about the effects of blood rheology on the occurrence of acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia and hemoglobin SC disease.Design and Methods To address this issue, steady ...
Yann Lamarre, Marc Romana, Xavier Waltz, Marie-Laure Lalanne-Mistrih, Benoît Tressières, Lydia Divialle-Doumdo, Marie-Dominique Hardy-Dessources, Jens Vent-Schmidt, Marie Petras, Cedric Broquere, Frederic Maillard, Vanessa Tarer, Maryse Etienne-Julan, Philippe Connes   +13 more
doaj   +1 more source

Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population [PDF]

Genetics and Molecular Biology, 2020
Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease.
Cristian Fong, Yesica Mendoza, Guillermo Barreto   +2 more
doaj   +1 more source