Results 71 to 80 of about 247,564 (312)

Automated screening of sickle cells using a smartphone-based microscope and deep learning [PDF]

open access: yesnpj Digital Medicine (2020), 2019
Sickle cell disease (SCD) is a major public health priority throughout much of the world, affecting millions of people. In many regions, particularly those in resource-limited settings, SCD is not consistently diagnosed. In Africa, where the majority of SCD patients reside, more than 50% of the 0.2-0.3 million children born with SCD each year will die ...
arxiv   +1 more source

Coexisting Cardiac and Hematologic Disorders. [PDF]

open access: yes, 2016
Patients with concomitant cardiac and hematologic disorders presenting for noncardiac surgery are challenging. Anemic patients with cardiac disease should be approached in a methodical fashion.
Goldhammer, Jordan E., Kohl, Benjamin A.
core   +3 more sources

Liver Cirrhosis in a Patient with Sickle Cell Trait (Hb Sβ+ Thalassemia) without Other Known Causes of Hepatic Disease

open access: yesCase Reports in Gastroenterology, 2009
Liver involvement in patients with sickle cell anemia/trait includes a wide range of alterations, from mild liver function test abnormalities to cirrhosis and acute liver failure. Approximately 15–30% of patients with sickle cell anemia present cirrhosis
Luca Santi   +7 more
doaj   +1 more source

Influence of ?S-globin haplotypes and hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2014
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino   +5 more
doaj   +1 more source

Safety and efficacy of blood exchange transfusion for priapism complicating sickle cell disease. [PDF]

open access: yes, 2016
BACKGROUND: Priapism is unwanted painful penile erection that affects about 36% of boys and men with sickle cell disease (SCD) most of whom have sickle cell anemia. Clinically, priapism could be stuttering, minor, or major.
Adeyoju   +23 more
core   +2 more sources

Adverse effect of hydroxyurea on spermatogenesis in patients with sickle cell anemia after 6 months of treatment.

open access: yesBlood, 2017
To the editor: The prognosis of sickle cell anemia (SCA), initially disastrous in the severe forms of the disease, has greatly improved, leading to increased life expectancy. More than 95% to 99% of the children diagnosed with SCA in developed countries
I. Berthaut   +14 more
semanticscholar   +1 more source

Haploidentical HSCT for hemoglobinopathies: improved outcomes with TCRαβ+/CD19+-depleted grafts

open access: yesBlood Advances, 2018
: We examined outcomes of haploidentical hematopoietic cell transplantation (haplo-HCT) using T-cell receptor αβ+ (TCRαβ+)/CD19+-depleted grafts (TCR group, 14 patients) in children with hemoglobinopathies.
Javid Gaziev   +11 more
doaj  

The Virginia Sickle Cell Anemia Awareness Program: Education, Screening, and Counseling [PDF]

open access: yes, 1977
In 1968, a program of screening for sickle trait carriers was begun as part of the work of the Hematology Division, Department of Medicine, at the Medical College of Virginia.
Cooper, Florence N., Scott, Robert B.
core   +1 more source

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

open access: yes, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST   +5 more
core   +1 more source

Hemoglobin E Disorders in South Gujarat – A Study Of 35 Cases

open access: yesNational Journal of Community Medicine, 2012
Background:Among the inherited disorders of blood, hemoglobinopathies and thalassemia constitute a major bulk of non-communicable genetic disease in India.
B M Jha   +3 more
doaj  

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