Results 141 to 150 of about 70,815 (255)
A global survey of blood transfusion practices for patients with sickle cell disease
Abstract Background Sickle cell disease (SCD) affects over 7 million people globally, with blood transfusion remaining a cornerstone of management. However, contemporary transfusion practices across diverse settings remain poorly characterized. We evaluated global transfusion practices for patients with SCD to identify gaps and inform resource ...
Jeremy W. Jacobs +18 more
wiley +1 more source
Transthyretin V122I variant and protein affect cardiac severity and mortality in sickle cell disease. [PDF]
Li H +9 more
europepmc +1 more source
Abstract Background In Canada, blood operators permanently defer individuals with a history of malaria to prevent transfusion‐transmitted malaria. While protective, this policy raises equity concerns, particularly for individuals requiring frequent transfusions, including those living with sickle cell disease.
N. Joëlle Kasongo +4 more
wiley +1 more source
Contrast-Associated AKI in Hospitalized Adults With Sickle Cell Disease. [PDF]
Azoyan L +10 more
europepmc +1 more source
Public perspectives on potential changes to malaria deferral criteria in Canada
Abstract Background and Objectives As blood collection agencies (BCAs) seek to increase donor diversity, making changes to eligibility criteria to enable more people to donate is an important consideration. BCAs in Canada have a permanent deferral from whole blood and platelet donation for anyone with a history of malaria, a barrier to donation for ...
Courtney Joshua +4 more
wiley +1 more source
Cerebral microhemorrhages in a mouse model of sickle cell disease. [PDF]
Hung YH +10 more
europepmc +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Plasma proteome signatures are predictive of mortality in sickle cell disease. [PDF]
Chignon A +4 more
europepmc +1 more source
Abstract Arterial shear‐mediated vasodilation is a well‐established measure of endothelial function and serves as a critical biomarker for cardiovascular disease risk. Endothelial function can be measured using a variety of experimental methodologies; however, the most widely adopted technique is ultrasound‐based flow‐mediated dilation (FMD), in which ...
Yi Zhen Bao +4 more
wiley +1 more source
India's digital-first approach to sickle cell disease elimination. [PDF]
Nair AR.
europepmc +1 more source

