Results 161 to 170 of about 70,815 (255)
Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi +11 more
wiley +1 more source
Cystic fibrosis and sickle cell disease associated with nonadministration of VTE prophylaxis in hospitalized adults. [PDF]
Caparon K +13 more
europepmc +1 more source
Abstract This article presents checklists designed to guide clinicians in the comprehensive management of pregnant individuals with sickle cell disease, including prepregnancy, antepartum, delivery, and postpartum care, as well as the specific management of vaso‐occlusive crises.
Society for Maternal‐Fetal Medicine (SMFM) +7 more
wiley +1 more source
Acute Chest Syndrome in Children with Sickle Cell Disease: A Narrative Review. [PDF]
Ramirez V, Mercier-Ross J.
europepmc +1 more source
Abstract A 41‐year‐old male patient presented with a 13‐year history of recurrent nocturnal penile pain associated with erections during sleep. Over the course of his illness, the patient attended outpatient clinics on 298 occasions and was hospitalized three times. The primary symptom reported was erectile pain occurring during sleep.
Liping Zhang +5 more
wiley +1 more source
Background and Purpose Sickle cell disease (SCD) is a hereditary blood disorder caused by mutation of β‐globin. In SCD, haemoglobin polymerization causes red blood cells to assume a rigid sickle‐shape leading to neurovascular alterations, including development of vascular dementia – characterized by cognitive impairment and reduced cerebral perfusion ...
Julia Zaccarelli‐Magalhães +11 more
wiley +1 more source
Hepatic Enzyme Abnormalities and Their Association With Hematological Parameters in Sickle Cell Disease: A Case-Control Study in Cameroon. [PDF]
Simo JL +6 more
europepmc +1 more source
ABSTRACT Aim This study aimed to summarize the current state of the science for “health service delivery–oriented outcomes” from nursing in genomics (2012–2025). Background Nurses can play a vital role in increasing access to genomic healthcare and improving outcomes for patients, families, and communities.
Jordan N. Keels +6 more
wiley +1 more source
Recruitment and retention of young adults with sickle cell disease. [PDF]
Belton T +19 more
europepmc +1 more source
Prevalence of Hepatitis B Virus Infection in Cameroon: A Systematic Review and Meta‐Analysis
ABSTRACT Chronic hepatitis B virus (HBV) infection is a global public health problem, and many regions of Sub‐Saharan Africa are disproportionately affected, including Cameroon, where prevalence has previously been shown to be high. This study aimed to provide up‐to‐date estimates of HBV prevalence in Cameroon.
Iya Maliki +4 more
wiley +1 more source

