Results 151 to 160 of about 70,815 (255)

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

Risk factors for venous thromboembolism in sickle cell disease. [PDF]

Res Pract Thromb Haemost
Bhasin N, Zhang L, Ajayi A, Patel S, Imai T, Agarwal S.   +5 more
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

First Antibiotic Prophylaxis Prescription Among Children With Sickle Cell Disease.

JAMA Pediatr
Shi JS, LaFon E, Sutaria A, Attell BK, Zhou M, Tang A, Snyder AB.   +6 more
europepmc   +1 more source

Sustainment of Hydroxyurea Adherence in Patients With Sickle Cell Disease.

JAMA Netw Open
Heitzer AM, Wooten Z, Luo G, Treadwell M, King AA, Gordeuk VR, Shah N, Abrams CM, McCuskee S, Gollan S, Longoria J, Hankins JS, Sickle Cell Disease Implementation Consortium.   +12 more
europepmc   +1 more source

Rethinking Sickle Cell Disease as a Systemic Vasculopathy. [PDF]

Cells
DuPont M, Galadanci NA, Patel RV, Lebensburger J, Kanter J.   +4 more
europepmc   +1 more source

Undetectable Hydroxyurea Levels in the Majority of Sickle Cell Disease Patients, Especially in Young Children

American Journal of Hematology, Volume 101, Issue 9, Page 2297-2310, September 2026.
ABSTRACT Hydroxyurea (HU) is the most widely prescribed disease‐modifying treatment in sickle cell disease (SCD), though treatment responses vary due to metabolism and adherence. We examined HU blood levels and treatment response in patients with homozygous sickle cell disease (HbSS).
Sigrid van der Veen, Bart J. Biemond, Marjon H. Cnossen, Pablo Bartolucci, Maria P. Boaro, Betzabel Cajiao Garcia, Raffaella Colombatti, M. D'Agnolo, Karin Fijnvandraat, Anna Collado Gimbert, Amira Idrizovic, Petros Kountouris, Mar Mañú‐Pereira, Elisabetta Mezzalira, Mariane de Montalembert, Erfan Nur, A. Pham Hung D' Alexandry D'Orengiani, Tiziana Sanavia, Saskia E. M. Schols, Marissa J. M. Traets, Minke A. E. Rab, Sara I. Reidel, Anita W. Rijneveld, Yosr Zaouali, Nanda M. Verhoeven‐Duif, Judith J. M. Jans, Eduard J. van Beers   +26 more
wiley   +1 more source

Determinants of clinical severity in children with sickle cell disease and confirmed asthma. [PDF]

PLoS One
Bafunyembaka G, Nacher M, Makembi A, Nathan N, Elenga N.   +4 more
europepmc   +1 more source

Cerebral Blood Transit in Sickle Cell Anemia

Journal of Magnetic Resonance Imaging, Volume 64, Issue 3, Page 738-750, September 2026.
ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Wesley T. Richerson, Megan A. Aumann, Alexander K. Song, Samantha Davis, Lauren Milner, Maria Garza, Dann Martin, L. Taylor Davis, Sumit Pruthi, Lori C. Jordan, Manus J. Donahue   +10 more
wiley   +1 more source

Hematopoietic Stem Cell Transplant and Brain Volume Changes in Adults With Sickle Cell Disease. [PDF]

Neurology
Kern KC, Inam Z, Hsieh MM, Tisdale JF, Fitzhugh CD, Limerick EM, Gebremeskel ASK, White T, Jordan LC, Lynch JK.   +9 more
europepmc   +1 more source