Results 171 to 180 of about 88,496 (299)

International multicentre evaluation of a new anti‐idiotypic anti‐daratumumab for resolving pre‐transfusion interferences

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Daratumumab, a therapeutic human anti‐CD38 monoclonal antibody, improves multiple myeloma outcomes but interferes with pre‐transfusion testing by binding CD38 on reagent red blood cells (RBCs), potentially masking clinically significant alloantibodies.
Arnaud Reggiani, Sofia Lejon Crottet, Sophie Waldvogel, Charlotte Engström, Serelina Coluzzi, Antonella Matteocci, Janis R. Hamilton, Levent Tufan Kumas, Karen M. K. de Vooght, Jill R. Storry, Jennylyn Flores, Núria Nogués, Carlos Cotorruelo, Molly Rutherford, Eveline B. Nilsen, Monika Pelc‐Kłopotowska, Jolanta Korzeniowska, Alessandra Baffa, Inna Sareneva, Nor Hafizah Ahmad, Katarzyna Szczudlo, Athif Rahman, Laser Sanal, Lise Jørgensen, Karolina Majewska Rochowiak, Monika Salwierz, Elisaveta Grancharova, Bojana Zivkovic, Jessica Alvarez, Mareike Riedl, Achim Knappik   +30 more
wiley   +1 more source

Transthyretin V122I variant and protein affect cardiac severity and mortality in sickle cell disease. [PDF]

Blood Adv
Li H, Gao S, Wang X, Asomaning N, Conrey A, Kruah B, Joo J, Wu CO, Sachdev V, Thein SL.   +9 more
europepmc   +1 more source

Molecular characterization of D variants in Brazilian blood donors and their association with RhCE and Duffy phenotypes

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Serological classification of RhD‐negative and weak D is often insufficient in admixed populations, where diverse RHD variants have clinical implications. In Brazil's highly admixed population, RhD interpretation and donor–recipient matching are particularly challenging.
Thamy C. S. Silva, Marcia R. Dezan, Sidneia Costa, Beatriz C. Girardo, Bruno R. Cruz, Karen Ziza, Dante M. Langhi, José O. Bordin, Lilian Castilho, Carla L. Dinardo   +9 more
wiley   +1 more source

Mitapivat for sickle cell disease: the time is ripe for a new therapy. [PDF]

Ann Transl Med
Cheng AN, Al-Samkari H.
europepmc   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Primum non nocere: the case against transplant for children with sickle cell anemia without progressive end-organ disease

Blood Advances, 2017
Michael R. DeBaun, Ellen Wright Clayton
doaj   +1 more source

Plasma proteome signatures are predictive of mortality in sickle cell disease. [PDF]

Blood Adv
Chignon A, Zaouali Y, Galactéros F, Bartolucci P, Lettre G.   +4 more
europepmc   +1 more source

Five Steps to Safer Blood Transfusions if You Have Sickle Cell Disease

If you have sickle cell disease (SCD), you may need one or more blood transfusions (healthy blood from a donor put into your body) during your lifetime. During a blood transfusion, your blood and the donated blood must have matching antigens, or special ...

core  

Branch retinal artery occlusion due to patent foramen ovale in a teenager

Experimental Physiology, EarlyView.
Abstract This report demonstrates the diagnostic evaluation and clinical management of a 16‐year‐old girl who developed branch retinal artery occlusion secondary to patent foramen ovale. The goal is to increase awareness of this rare presentation in adolescents among clinicians, with a summary of the important clinical features, multimodal imaging ...
Jie Zu, Fang Fan, Jiayao Wang, Jianmin Wang, Zhiyang Jia   +4 more
wiley   +1 more source

Cerebral microhemorrhages in a mouse model of sickle cell disease. [PDF]

J Sick Cell Dis
Hung YH, Fang C, Lee D, Yan J, Kiven S, Liu J, Kim SM, Paganini-Hill A, Cribbs DH, Gupta K, Fisher M.   +10 more
europepmc   +1 more source