Results 191 to 200 of about 94,881 (302)

Suspension physics govern the multiscale dynamics of blood flow in sickle cell disease. [PDF]

Sci Adv
Szafraniec HM, Bull F, Higgins JM, Stone HA, Krüger T, Pearce P, Wood DK.   +6 more
europepmc   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, Volume 36, Issue 5, 15 January 2026.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Newborn screening for sickle cell disease in Caluquembe, southwestern Angola, 2024-2025. [PDF]

PLoS One
Su JJ, Kupua VS, Cummings D, Jacobsen KH.   +3 more
europepmc   +1 more source

The impact of social vulnerability on primary vaccine coverage in children with sickle cell disease. [PDF]

Front Public Health
Shi JS, LaFon E, Sutaria A, Attell BK, Zhou M, Tang A, Snyder AB.   +6 more
europepmc   +1 more source

Ventricular hypertrophy and restrictive lung profile in young patients with sickle cell disease

, 2014
Osvaldo Alves de Menezes Neto
openalex   +1 more source

Ecologies of Risk: Malaria and Settler Landscape Transformation in 19th‐Century Ontario

American Journal of Human Biology, Volume 38, Issue 1, January 2026.
ABSTRACT Objectives This study examines how settler‐driven environmental change shaped malaria transmission and mortality in 19th‐century southern Ontario. It aimed to understand the biosocial and ecological conditions that sustained endemic malaria in a temperate, colonial context.
Amanda Cooke, Megan B. Brickley
wiley   +1 more source

Building a Comprehensive Sickle Cell Disease Program in Western Kenya: A Decade of Experience and Growth. [PDF]

Ann Glob Health
Njuguna F, Kilach C, Njuguna C, Ayaye E, Wanjiku C, Korir R, Bor C, Midiwo N, Aliwa E, Oburah E, Mbunya S, Kipkoech J, Etling MA, Severance T, Nessle CN, Vik T, Kumar M, Roberson C, Greist A.   +18 more
europepmc   +1 more source

Long-term follow-up demonstrates durable clinical benefits of exagamglogene autotemcel for sickle cell disease with recurrent vaso-occlusive crises: Final results of climb SCD-121 [PDF]

Stephan A. Grupp, Franco Locatelli, Akshay Sharma, Monica Bhatia, Markus Y. Mapara, Robert I. Liem, Laurence Dedeken, Lyndsay Molinari, Michael J. Eckrich, Kevin H.M. Kuo, Paul Telfer, Ami J. Shah, Marina Cavazzana, Selim Corbacioglu, Mariane de Montalembert, Stephan Lobitz, Damiano Rondelli, Martin H. Steinberg, Mark C. Walters, Kevin Boerner, Tina Liu, Suzan Imren, William Hobbs, Haydar Frangoul   +23 more
openalex   +1 more source

PROGRESSIVE COGNITIVE DECLINE IN ADULTS WITH SICKLE CELL DISEASE (SCD): THE EFFECTS OF THE SOCIOCULTURAL BACKGROUND AND CEREBRAL ATROPHY

, 2020
Bruno Deltreggia Benites, C.M. Silva, Brunno Machado de Campos, P.M. Campos, Samuel Souza Medina, Fernando Cendes, Sara Teresinha Olalla Saad   +6 more
openalex   +1 more source

Unveiling the Genetic Association Between Hemoglobin Concentration and Amyotrophic Lateral Sclerosis

Brain and Behavior, Volume 16, Issue 1, January 2026.
This study identified a causal relationship between genetically predicted hemoglobin (Hb) concentration and amyotrophic lateral sclerosis (ALS) through Mendelian randomization (MR), and integrated RNA‐seq and RT‐qPCR analyses to highlight BACH1, FLVCR1, and TRIM58 as potential genes involved in this association.
Hongmei Luo, Yujie Yang, Xiaojian Cao, Chunchu Deng, Hong Chen   +4 more
wiley   +1 more source