Results 231 to 240 of about 88,496 (299)

EHA Recommendations for preconceptual and antenatal screening and prenatal diagnosis for hemoglobinopathies

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Thalassemia and sickle cell disease (SCD) are among the most common monogenic disorders worldwide. They cause chronic hemolytic anemia, the consequences and prognosis of which vary considerably depending on the genetic characteristics of patients and the healthcare system in their country of residence.
Mariane de Montalembert, Maria D. Cappellini, Achille Iolascon, Lucia de Franceschi, Eda Ömur, Michele Abi Saad, Immacolata Andolfo, Celeste Bento, Maria Berghs, Doris Bonnet, Andreas Glenthoj, Beatrice Gulbis, Tuphan K. Dolai, Jorge Lima, Irene Motta, Roberta Russo, Ali Taher, Leon Tshilolo, Antonio Almeida, David Rees   +19 more
wiley   +1 more source

Ferroportin inhibition attenuates pulmonary hypertension in hypoxic sickle cell disease mice. [PDF]

Blood Adv
Lucero MJ, Setua S, Thangaraju K, Khan A, Lamb DR, Lisk C, Swindle D, Cendali FI, Dzieciatkowska M, Stephenson D, Pak DI, Tolson R, Zaeske S, Rana NK, Khan S, Westover N, Davizon-Castillo P, George G, Hassell K, Nuss R, D'Alessandro A, Manolova V, Irwin DC, Buehler PW.   +23 more
europepmc   +1 more source

Iptacopan monotherapy resulted in increased hemoglobin level in patients with PNH and hemoglobin ≥10 g/dL after anti‐C5 therapy

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Patients with paroxysmal nocturnal hemoglobinuria (PNH) on anti‐C5 often experience extravascular hemolysis with anemia. Iptacopan, the first oral proximal complement inhibitor targeting factor B, has shown efficacy and safety in PNH patients. APPULSE‐PNH (NCT05630001), a phase 3b, single‑arm, open‐label trial, enrolled adult patients with PNH
Austin Kulasekararaj, Flore S. de Fontbrune, Anna Gaya, Ilene Weitz, David J. Kuter, Bhumika J. Patel, David J. Araten, Abhay Singh, Jun H. Jang, Richard J. Kelly, Eros Di Bona, Michael Loschi, Vinod Pullarkat, Jörg Schubert, Rosario Notaro, Mustafa N. Yenerel, Joan Beckman, Nicolas Blin, Irina Murakhovskaya, Jens Panse, Eloy Roman, Alexander Röth, Hubert Schrezenmeier, Srinivas Tantravahi, Régis P. de Latour, Navin Mahajan, Luca Monaco, Tao Ding, Tomasz Lawniczek, Philippe Ferber, Marion Dahlke, Antonio M. Risitano   +31 more
wiley   +1 more source

Knowledge, Attitude, and Practice of Sickle Cell Disease Among Sickle Cell Disease Patients in Sudurpashchim Province of Nepal: A Cross-Sectional Study. [PDF]

Health Sci Rep
Joshi GD, Kamar SB, Mishra P, Pandey H, Rimal S, Shah Y, Tiwari RM, Mandal AK, Singh AK, Dumre SP, Pandey K, Khanal ED, Pandey BD, Marasini BP, Joshi P.   +14 more
europepmc   +1 more source

G‐CSF for Mobilizing CD34+ Cells in Individuals With SCD: A Word of Caution

American Journal of Hematology, Volume 101, Issue 6, Page 1178-1181, June 2026.
Akshay Sharma, Allistair Abraham, Monica Bhatia, María Cancio, Sonali Chaudhury, Selim Corbacioglu, Gregory M. T. Guilcher, Ashish O. Gupta, Rabi Hanna, Matthew M. Heeney, Tami John, Lakshmanan Krishnamurti, James L. LaBelle, Hemalatha G. Rangarajan, Shalini Shenoy, Elizabeth Stenger, Crawford Strunk, Courtney D. Fitzhugh   +17 more
wiley   +1 more source

Daprodustat augments red cell and γ-globin production in models of sickle cell disease. [PDF]

Blood Red Cells Iron
Sharma M, Ishfaq M, Mondal P, Mohideen A, Chowdhury FA, Taiclet S, Philips BJ, Crosby D, Wood KC, Straub AC, Ghosh S, Yien YY, Xu JZ.   +12 more
europepmc   +1 more source

Creative and Adaptive Solutions for Early Diagnosis of Sickle Cell Disease in Sub-Saharan Africa. [PDF]

Am J Hematol
Smart LR, Segbefia CI, Odame I.
europepmc   +1 more source

Clinical, humanistic, and economic burden of sickle cell disease in The Jazan Region, Saudi Arabia. [PDF]

PLoS One
Meraya AM, Banji OJF, Menachery SJ, Malhan HMA, Halawi HAA, Moraya D, Hakami HA, Kubayni AM, Alfaifi YY, Ghareeb HI, Rasayn MAA, Alfaifi RA.   +11 more
europepmc   +1 more source

Debunking myths: sickle cell trait, crises, and sudden death

Blood Advances
Michael R. DeBaun, Corey J. Hebert, Yvette M. Miller   +2 more
doaj   +1 more source