Results 21 to 30 of about 9,174,709 (287)

Development of multi-level standards of care recommendations for sickle cell disease: Experience from SickleInAfrica

Frontiers in Genetics, 2023
Introduction: Sickle Cell Disease (SCD) causes significant morbidity and mortality particularly in sub-Saharan Africa (SSA) where it contributes to early childhood deaths.
Vivian Paintsil, Vivian Paintsil, Mwashungi Ally, Hezekiah Isa, Kofi A. Anie, Josephine Mgaya, Malula Nkanyemka, Victoria Nembaware, Yaa Gyamfua Oppong-Mensah, Flora Ndobho, Lulu Chirande, Abel Makubi, Obiageli Nnodu, Ambroise Wonkam, Julie Makani, Kwaku Ohene-Frempong   +15 more
doaj   +1 more source

Osteoporosis in thalassaemia

Thalassemia Reports, 2018
Osteoporosis is a prominent cause of morbidity in patients with thalassaemia major (TM) with a complex pathophysiology. Patients with TM and osteoporosis have elevated markers of bone resorption.
Ersi Voskaridou, Maria Dimopoulou, Evangelos Terpos   +2 more
doaj   +1 more source

Sickle cell disease [PDF]

Clinical Medicine, 2001
SCD is a major health problem requiring lifelong multidisciplinary care to manage the wide range of medical and social consequences. A number of new approaches offer the potential to have an impact on the natural history of this disease.
A, Yardumian, C, Crawley
openaire   +2 more sources

The patient as a partner in promoting healthcare policies and research

Thalassemia Reports, 2014
Not ...
Marco Bianchi, on behalf of Thalassaemia International Federation   +1 more
doaj   +1 more source

RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice

Haematologica, 2018
Sickle cell disease patients are at increased risk of developing a chronic kidney disease. Endothelial dysfunction and inflammation associated with hemolysis lead to vasculopathy and contribute to the development of renal disease.
Alfia Khaibullina, Elena A. Adjei, Nowah Afangbedji, Andrey Ivanov, Namita Kumari, Luis E.F. Almeida, Zenaide M.N. Quezado, Sergei Nekhai, Marina Jerebtsova   +8 more
doaj   +1 more source

Barriers to Therapeutic Use of Hydroxyurea for Sickle Cell Disease in Nigeria: A Cross-Sectional Survey

Frontiers in Genetics, 2022
Background: Sickle cell disease, the inherited blood disorder characterized by anemia, severe pain and other vaso-occlusive complications, acute chest syndrome, disproportionate hospitalization, and early mortality, has significant financial, social, and
Emmanuel Chide Okocha, Joyce Gyamfi, Nessa Ryan, Oluwatoyin Babalola, Eno-Abasi Etuk, Reuben Chianumba, Maxwell Nwegbu, Hezekiah Isa, Anazoeze Jude Madu, Samuel Adegoke, Uche Nnebe-Agumandu, Biobele Brown, Emmanuel Peprah, Obiageli E. Nnodu   +13 more
doaj   +1 more source

Transition Readiness of Pediatric Sickle Cell Patients to Adult Clinic in a Teaching Hospital, Ghana

Advances in Hematology
Conclusion: The study revealed a high transition readiness among pediatric patients. In general, the patients had high confidence transitioning to an adult clinic and the ability to manage their own healthcare.
Aaron Kwasi Nartey, Vivian Paintsil, Isaac Nyanor, Yaa Gyamfua Oppong-Mensah, Evans Xorse Amuzu, Eunice Agyeman Ahmed, Suraj Yawnumah Abubakar, Alex Osei-Akoto   +7 more
doaj   +1 more source

Neuroimaging Biomarkers in Paediatric Sickle Cell Disease [PDF]

, 2015
Sickle Cell Disease (SCD) is a collection of genetic haemoglobinopathies, the most common and severe being homozygous sickle cell anaemia. In the UK, it has been estimated that 1 in 2000 children are born with SCD. The disease is characterised by chronic
Kawadler, JM
core  

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source