Results 21 to 30 of about 178,306 (248)
Bacterial Infection in the Sickle Cell Population: Development and Enabling Factors
Microorganisms, 2023 The high frequency of bacterial infections represents a major threat to public health. In developing countries, they are still responsible for significant morbidity and mortality in pediatric populations with sickle cell disease, particularly in children
Lucrèce M. Délicat-Loembet +3 more
doaj +1 more source
Successful orthotopic liver transplantation in an adult patient with sickle cell disease and review of the literature [PDF]
, 2013 Sickle cell disease can lead to hepatic complications ranging from acute hepatic crises to chronic liver disease including intrahepatic cholestasis, and iron overload.
Blinder, Morey A. +7 more
core +2 more sources
Leg ulcers in sickle cell disease. [PDF]
, 2010 Sickle cell disease is a single amino acid molecular disorder of hemoglobin leading to its pathological polymerization, red cell rigidity that causes poor microvascular blood flow, with consequent tissue ischemia and infarction.
Ballas, Samir K. +4 more
core +2 more sources
Disease knowledge and health literacy in parents of children with sickle cell disease
eJHaem, 2023 We aimed to (1) describe sickle cell disease (SCD) knowledge and health literacy levels in parents of children with SCD, (2) examine associations with socio‐demographic factors and (3) analyse the association with hospital admissions and frequency of ...
Bonaventure G. Ikediashi +3 more
doaj +1 more source
Frontiers in Genetics, 2023 Introduction: Sickle Cell Disease (SCD) causes significant morbidity and mortality particularly in sub-Saharan Africa (SSA) where it contributes to early childhood deaths.
Vivian Paintsil +15 more
doaj +1 more source
Clinical Medicine, 2001 SCD is a major health problem requiring lifelong multidisciplinary care to manage the wide range of medical and social consequences. A number of new approaches offer the potential to have an impact on the natural history of this disease.
A, Yardumian, C, Crawley
openaire +2 more sources
Comorbidities in aging patients with sickle cell disease. [PDF]
, 2018 Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core +2 more sources
Elevated pulse pressure is associated with hemolysis, proteinuria and chronic kidney disease in sickle cell disease [PDF]
, 2014 A seeming paradox of sickle cell disease is that patients do not suffer from a high prevalence of systemic hypertension in spite of endothelial dysfunction, chronic inflammation and vasculopathy.
Gladwin, MT +6 more
core +1 more source
The Neonatal Screening Program in Brazil, Focus on Sickle Cell Disease (SCD)
International Journal of Neonatal Screening, 2019 Since 2001, the Brazilian Ministry of Health has been coordinating a National Neonatal Screening Program (NNSP) that now covers all the 26 states and the Federal District of the Brazilian Republic and targets six diseases including sickle cell disease ...
Ana C. Silva-Pinto +4 more
doaj +1 more source
Thalassemia Reports, 2018 Osteoporosis is a prominent cause of morbidity in patients with thalassaemia major (TM) with a complex pathophysiology. Patients with TM and osteoporosis have elevated markers of bone resorption.
Ersi Voskaridou +2 more
doaj +1 more source