Results 41 to 50 of about 178,306 (248)

Erythroid Adhesion Molecules in Sickle Cell Anaemia Infants: Insights Into Early Pathophysiology

EBioMedicine, 2015
Sickle cell anaemia (SCA) results from a single mutation in the β globin gene. It is seldom symptomatic in the first semester of life. We analysed the expression pattern of 9 adhesion molecules on red blood cells, in a cohort of 54 SCA and 17 non-SCA ...
Valentine Brousse, Yves Colin, Catia Pereira, Cecile Arnaud, Marie Helene Odièvre, Anne Boutemy, Corinne Guitton, Mariane de Montalembert, Claudine Lapouméroulie, Julien Picot, Caroline Le Van Kim, Wassim El Nemer   +11 more
doaj   +1 more source

HIV-1 Transcription Inhibitor 1E7-03 Restores LPS-Induced Alteration of Lung Leukocytes’ Infiltration Dynamics and Resolves Inflammation in HIV Transgenic Mice

Viruses, 2020
Human immunodeficiency virus (HIV)-infected individuals treated with anti-retroviral therapy often develop chronic non-infectious lung disease. To determine the mechanism of HIV-1-associated lung disease we evaluated the dynamics of lung leukocytes in ...
Marina Jerebtsova, Asrar Ahmad, Xiaomei Niu, Ornela Rutagarama, Sergei Nekhai   +4 more
doaj   +1 more source

Reaching Community Through School Going Children for Sickle Cell Disease in Zankhvav Village of Surat District, Western India [PDF]

, 2012
Objectives: The objective of the study was to explore a method to reach the community via school going adolescents for screening tribal people for Sickle Cell disease.
Bansal, R, Gharat, VV, Mallick, KH, Rupani, MP, Vasava, BC   +4 more
core   +1 more source

Safety and efficacy of blood exchange transfusion for priapism complicating sickle cell disease. [PDF]

, 2016
BACKGROUND: Priapism is unwanted painful penile erection that affects about 36% of boys and men with sickle cell disease (SCD) most of whom have sickle cell anemia. Clinically, priapism could be stuttering, minor, or major.
Adeyoju, Ayache, Ballas, Ballas, Baron, Betke, Charache, Eckman, Emond, Harms, Janes, Mantadakis, Okpala, Powars, Rackoff, Rogers, Seeler, Serjeant, Serjeant, Sharpsteen, Siegel, Talacki, Teixeira, US Department of Health and Human Services   +23 more
core   +2 more sources

Awareness, attitude, and acceptance of newborn screening for sickle cell disease among health workers and caregivers at primary healthcare centers in Gwagwalada Area Council, Federal Capital Territory, Abuja, Nigeria

Frontiers in Public Health
IntroductionNewborn Screening (NBS) is a public health program designed to identify and provide early interventions for infants with genetic disorders such as Sickle Cell Disease (SCD).
Isa Hezekiah A, Chisomaga Ifeanyi Oparaugo, Grace Doyin Ajetomobi, Ayomide Esther Fasina, Reuben Ikechukwu Chianumba, Obiageli Eunice Nnodu, Obiageli Eunice Nnodu   +6 more
doaj   +1 more source

Sickle-cell disease [PDF]

Nature, 2014
Lauren, Gravitz, Stephen, Pincock
  +6 more sources

The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]

, 2020
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core   +1 more source

Primary stroke in a woman with sickle cell anemia responsive to hydroxyurea therapy. [PDF]

, 2014
The most common cause of stroke in children with sickle cell anemia is infarction due to ischemia. In adults, however, stroke is most commonly hemorrhagic in nature. Other causes of stroke in patients with sickle cell disease are very rare. In this short
Ballas, Samir K., Martinez-Outshoorn, Ubaldo E., Savage, Michael P   +2 more
core   +2 more sources

Pulmonary hypertension in adolescents with sickle cell disease [PDF]

, 2016
Sickle cell disease consists of a group of disorders that have a similar mutation in at least one of the beta-globin chains of hemoglobin. This results in a change of the hemoglobin to sickle shaped cells when in the deoxygenated state.
Akinyemi, Katherine
core   +1 more source

Sickle cell trait and risk of cognitive impairment in African-Americans: The REGARDS cohort [PDF]

, 2019
Background: Sickle cell anemia may be associated with cognitive dysfunction, and some complications of sickle cell anemia might affect those with sickle cell trait (SCT), so we hypothesized that SCT is a risk factor for cognitive impairment. Methods:
Cahill, Christina R., Cushman, Mary, Hyacinth, Hyacinth I., Irvin, Marguerite Ryan, Judd, Suzanne E., Leach, Justin M., Manly, Jennifer, McClure, Leslie A., Naik, Rakhi, Unverzagt, Frederick, Wadley, Virginia G., Winkler, Cheryl, Zakai, Neil A.   +12 more
core   +1 more source