Results 41 to 50 of about 9,174,709 (287)
American Journal of Community Psychology, EarlyView.Abstract Firefighters face an array of stressors due to the demands of their occupation, leading to a high prevalence of mental health challenges. Social prescribing represents a novel approach to healthcare that emphasizes a holistic view of health and wellbeing.
Janice Ikeda +2 more
wiley +1 more source
Get screened for sickle cell trait [PDF]
Know Your StatusDid you know there\u2019s more than one way to inherit Sickle Cell Disease?If you don\u2019t have a health care provider, visit our Sickle Cell Disease National Resource Directory at www.cdc.gov/ncbddd/sicklecellSickle Cell Disease ...
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American Journal of Hematology, EarlyView.ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga +58 more
wiley +1 more source
, 2019 Sickle cell disease (SCD) is a group of inherited blood disorders that cause severe pain, reduce life expectancy and require significant self-management, but are often associated with stigma and discrimination.
Elander, James
core
Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case-control study. [PDF]
, 2009 BACKGROUND: In sub-Saharan Africa, more than 90% of children with sickle-cell anaemia die before the diagnosis can be made. The causes of death are poorly documented, but bacterial sepsis is probably important.
Uyoga, Sophie +44 more
core +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Although circulating nucleated red blood cells (cNRBCs) have previously been detected in patients with sickle cell disease (SCD), their prevalence and clinical significance during steady‐state disease have not been established. We retrospectively analyzed 270 adults with an SS or Sβ0‐thalassemia genotype.
Ugo Boccadifuoco +7 more
wiley +1 more source
Biomarkers in sickle cell disease [PDF]
British Journal of Haematology, 2011 SummaryMore than 100 different blood and urine biomarkers have been described in sickle cell disease (SCD), with the number increasing rapidly as analytical techniques develop. Nearly all of these biomarkers are abnormal in the steady state, and become more so during complications.
Rees, David C., Gibson, John S.
openaire +3 more sources
Annals of Neurology, EarlyView.Objective Glycosylphosphatidylinositol (GPI)‐anchored proteins play critical roles in nervous system function. Pathogenic variants in genes involved in GPI‐anchor biosynthesis cause early‐onset multisystem disorders known as inherited GPI deficiencies. We describe a novel neuromuscular phenotype associated with PIGB deficiency.
Gorka Fernández‐Eulate +34 more
wiley +1 more source
Stroke without cerebral arteriopathy in sickle cell disease children: causes and treatment
HaematologicaCerebral arteriopathy (CA) in children with sickle cell disease (SCD) is classically described as chronic stenosis of arteries in the anterior brain circulation, leading to ischemic stroke. Some studies have however reported strokes in children with SCD
Sarah Liane Linguet +10 more
doaj +1 more source
Macrophage HIV-1 Gene Expression and Delay Resolution of Inflammation in HIV-Tg Mice
Viruses, 2020 While antiretroviral therapy increases the longevity of people living with HIV (PLWH), about 30% of this population suffers from three or more concurrent comorbidities, whose mechanisms are not well understood.
Marina Jerebtsova +4 more
doaj +1 more source