Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]
BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
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Insights Into Elevated Distortion Product Otoacoustic Emissions In Sickle Cell Disease: Comparisons of Hydroxyurea-treated and Non-treated Young Children [PDF]
Distortion product otoacoustic emissions (DPOAEs) were examined in 15 normal- hearing African-American children between the ages of 6 and 14 years with homozygous sickle cell disease (SCD), who were on a regimen of hydroxyurea (HDU), a drug that reduces ...
Adams +75 more
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SICKLE CELL DISEASE AND PREGNANCY
Abstract Sickle Cell Disease (SCD) is a group of inherited single-gene autosomal recessive disorders caused by the ‘sickle’ gene, which affects haemoglobin structure. Sickle cell anemia is the most common hemoglobinopathy worldwide. The burden of sickle cell disease in pregnancy has been exponentially increasing with more number of women ...
Dipty Jain +4 more
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Sickle cell disease (SCD) imposes a significant health burden, particularly in low- and middle-income countries where healthcare professionals and resources are scarce.
Paul Muteb Boma +3 more
doaj +1 more source
Biologic Assessment of RBC Biology and Neutrophil Activation: Correlation with Sickle Cell Disease Activity [PDF]
Marilyn J. Telen +2 more
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Exertional sickling: Questions and controversy [PDF]
Sickle cell trait (SCT) occurs in about 8% of African-Americans and is often described to be of little clinical consequence. Over time, a number of risks have emerged, and among these are rare but catastrophic episodes of sudden death in athletes and ...
Blinder, Morey A., Russel, Sarah
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Thrombosis and Sickle Cell Disease
Sickle cell disease (SCD) is characterized by the presence of sickle hemoglobin, which has the unique property of polymerizing when deoxygenated. The pathophysiology of acute and chronic clinical manifestations of SCD have shown the central role of dense, dehydrated red cells in acute and chronic clinical manifestations of this pathology.
DE FRANCESCHI, Lucia +2 more
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SICKLE CELL DISEASE - CASE REPORTS
Sickle cell diseases are inherited hematological diseases, prevalent in certain parts of the world. We report two cases of sickle cell diseases, first being sickle cell b-thalassaemia and second homozygous sickle cell disease (SS).
Ram Chandra Adhikari +5 more
doaj +1 more source
Vascular Function Intervention Trial in sickle cell disease (V-FIT): Trial Protocol [PDF]
This protocol outlines procedures for capturing participant information as part of the V-FIT study. The protocol should not be used as a guide for the treatment of other participants; every care was taken in its drafting, but corrections or amendments ...
Cox, Sharon +3 more
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Microalbuminuria as Predictor of Early Glomerular Injury in Children and Adolescents with Sickle Cell Anaemia at Muhimbili National Hospital Dar es Salaam, Tanzania 2012 [PDF]
Microalbuminuria (MA) is the earliest marker of various diseases affecting the renal system. Its relevance in children and adolescents with sickle cell anaemia (SCA), who are known to be prone to renal complications, has not been fully explored in our ...
Christopher, Richard
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