Results 71 to 80 of about 70,815 (255)

Association between maternal pre‐pregnancy body mass index and maternal and neonatal outcomes in Saudi Arabia: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) of the mother before pregnancy and the growth of weight during pregnancy are both important perinatal health determinants. The aim of the present study was to examine the association between the maternal BMI and obstetric and ...
Randa Elsayed   +7 more
wiley   +1 more source

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

open access: yesFrontiers in Microbiology, 2019
Ebola virus (EBOV) is a non-segmented negative-sense RNA virus that causes a severe human disease. The ongoing EBOV outbreak in the Eastern part of Democratic Republic of the Congo has resulted to date in over 2500 confirmed cases including over 1500 ...
Xionghao Lin   +16 more
doaj   +1 more source

Fetal growth trajectories and neonatal outcomes: A French population‐based study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study assesses whether fetal growth trajectories are associated with neonatal outcomes. Methods The study population included 8537 singleton liveborn infants from the 2021 French National Perinatal Survey. Fetal growth trajectories were assessed between second and third trimester routine ultrasounds and between the third ...
Pierre Gibert   +22 more
wiley   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

open access: yesiMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang   +19 more
wiley   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari   +3 more
wiley   +1 more source

Findings supporting neonatal screening for sickle cell disease: an observational study in Senegal

open access: yesFrontiers in Pediatrics
IntroductionSickle cell disease (SCD) is a major contributor to morbidity and mortality in sub-Saharan Africa, and early detection through neonatal screening can improve outcomes. In Senegal, systematic screening is not yet implemented.
Lucie Petigas   +8 more
doaj   +1 more source

Qualitative and Quantitative Microbiological Studies of Paediatric Artemether-Lumefantrine Dry Powders and Paracetamol Syrups Obtained from Selected Drug Stores in Accra, Ghana

open access: yesJournal of Tropical Medicine, 2019
Infants and children under five years generally have high susceptibility to pathogenic and opportunistic infections due to immaturity and inexperience of their immune responses.
Solomon Opoku, Isaac Nyanor
doaj   +1 more source

Head shape determination and cranial evaluation using anatomical landmarks in children with sickle cell disease (SCD)

open access: yesAsian Journal of Medical Sciences, 2014
Background: Sickle cell disease is one of the commonest diseases widespread in sub-Saharan Africa and Nigeria in particular. This study investigated the possible effects of sickle cell disease (SCD) on the cranial index and pattern of head shapes of ...
MA Musa
doaj   +1 more source

Mapping the subgingival HerBiome and HisBiome over the human healthspan

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam   +3 more
wiley   +1 more source

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