Results 91 to 100 of about 9,174,709 (287)

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

Fonio (Digitaria exilis and Digitaria iburua) in Nigeria: Regional cultivation patterns, landrace diversity, and farmer knowledge for conserving a climate‐resilient indigenous cereal

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Fonio (Digitaria exilis and Digitaria iburua) cereals are valued for their drought resilience, adaptability to poor soils, and cultural importance. In Nigeria, where both species are cultivated, fonio has declined due to labor‐intensive processing, lower yields, and changing livelihood choices. By documenting 21 landraces (15 D. exilis and 6 D. iburua),
Ishaq Muawiyya   +4 more
wiley   +1 more source

Genome Analysis of Corynebacterium ulcerans Isolates Chronologically Recovered From the Same Cat for Two Years: Circulation in a Cat Shelter

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Toxigenic Corynebacterium ulcerans, a zoonotic pathogen, was isolated repeatedly from a cat in an in‐house group in Japan. Although the cat was cured once by antibiotic treatment, clonal isolates of the original pathogenic strain were recovered repeatedly during a 2‐year course.
Ryoko Jikihara   +8 more
wiley   +1 more source

Three Tips for Safe Use of Medicines for People with Sickle Cell Disease

open access: yes
People with sickle cell disease (SCD) are often prescribed medicines for common complications of SCD.CS 319852-APublication date from document properties.sickle-cell-3-tips-safe-med-use-h ...

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Comparison of Definitions of Severe Maternal Morbidity: A National Cohort Study Using Administrative Data

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To understand agreement between definitions of severe maternal morbidity (SMM), the reasons for disagreement and the impact the outcome definition may have on the measurement of ethnic and socioeconomic inequalities. Design A national cohort study using administrative data. Setting The English National Health Service.
Ian Henderson   +3 more
wiley   +1 more source

Comparative Outcomes of Early versus Delayed Penile Prosthesis Insertion in Patients With Ischaemic Priapism—Long‐Term Outcome Experience From a Single High‐volume Centre

open access: yesAndrology, EarlyView.
ABSTRACT Background and Objectives Ischaemic priapism (IP) is a urological emergency that can lead to erectile dysfunction (ED) if not treated promptly. This study aims to evaluate and compare clinical outcomes between early and delayed penile prosthesis insertion in patients with IP.
King Sum Tong   +5 more
wiley   +1 more source

A study of 28 pregnant women with sickle cell disease and COVID-19: elevated maternal and fetal morbidity rates

open access: yesHaematologica, 2023
Laure Joseph   +12 more
doaj   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

open access: yesAndrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli   +7 more
wiley   +1 more source

Long‐Term Outcomes After Elective Splenectomy for Haematological Disease: A 27‐Year Single‐Centre Study

open access: yesANZ Journal of Surgery, EarlyView.
Splenectomy is a safe and effective treatment option in selected patients with haematological disease, despite declining referrals over the last 27 years in the era of targeted therapies. Outcomes are favourable when performed laparoscopically and long‐term follow‐up demonstrates sustained haematologic benefit in surviving patients.
Salil Dutt Barrett   +9 more
wiley   +1 more source

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