Results 71 to 80 of about 1,352,611 (298)

Self-assembly in solution of a reversible comb-shaped supramolecular polymer [PDF]

, 2010
We report a single step synthesis of a polyisobutene with a bis-urea moiety in the middle of the chain. In low polarity solvents, this polymer self-assembles by hydrogen bonding to form a combshaped polymer with a central hydrogen bonded backbone and ...
Abed S., Arnaud A., Bellot M., Berl V., Bernard J., Binder W. H., Binder W. H., Binder W. H., Binder W. H., Binder W. H., Boileau S., Bouteiller L., Bouteiller L., Brunsveld L., Casassa E. F., Ciferri A., Colombani O., Colombani O., Cordier P., Ducouret G., Ercolani G., Fang Z., Hammond M. R., Huang F., Ikkala O., Isare B., Isare B., Kato T., Kato T., Kato T., Knoben W., Knoben W., Lange R. F. M., Lortie F., Miyawaki A., Mueller M., Ohkawa H., Pinault T., Rosselli S., Ruokolainen J., Scherman O. A., Schirle M., Shikata T., Simic V., ten Brinke G., ten Cate A. T., Todd E. M., van der Gucht J., Vonau F., Yamaguchi N., Yount W. C.   +50 more
core   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

CD36‐Binding Amphiphilic Nanoparticles for Attenuation of α‐Synuclein‐Induced Microglial Activation

Advanced NanoBiomed Research, 2022
Neuroinflammation is one of the hallmarks contributing to Parkinson's disease (PD) pathology, where microglial activation occurs as one of the earliest events, triggered by extracellular α‐synuclein (aSYN) binding to the cluster of differentation 36 ...
Nanxia Zhao, Nicola L. Francis, Shuang Song, Vladyslav Kholodovych, Hannah R. Calvelli, Cody L. Hoop, Zhiping P. Pang, Jean Baum, Kathryn E. Uhrich, Prabhas V. Moghe   +9 more
doaj   +1 more source

Softening of the stiffness of bottlebrush polymers by mutual interaction

, 2007
We study bottlebrush macromolecules in a good solvent by small-angle neutron scattering (SANS), static light scattering (SLS), and dynamic light scattering (DLS).
Airaud, C., Ballauff, M., Bolisetty, S., Harnau, L., Lindner, P., Mueller, A. H. E., Rosenfeldt, S., Xu, Y.   +7 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Enhanced hydroxide conductivity in zwitterionic polyacrylate-based anion exchange membranes via side-chain length optimization

Green Energy & Environment
Developing advanced ion-conductive networks is crucial for anion exchange membranes (AEMs). A flexible molecular structure facilitates the formation of ion clusters, resulting in enhanced ionic conductivity.
Lu Cai, Naibing Li, Bingbing Li, Tianchi Zhou, Zhengyuan Zhou, Yongnan Zhou, Xi Luo, Kaiying Zhao, Yuekun Lai, Jinli Qiao   +9 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Procurement push and marketing pull in supply chain management: the conceptual contribution of relationship marketing as a driver in project financial performance [PDF]

, 2005
? The agenda for supply management practices on construction projects originated from clients. It is largely procurement driven, the dominant strategy of contractors being to emulate the client approach, and hence push the procurement model along the ...
Akintoye A., Christopher M., Druskatt V.U., Egan, Ford D., Green S., Grönroos C., Gummesson E., H Smyth, Handy C.B., Hoekstra S., Ive G., Latham, Levitt T., London K.R., London K.R., McGeorge D., Naylor B.J., Porter M.E., Smyth H.J., Smyth H.J., Smyth H.J., Smyth H.J., Smyth H.J., Smyth H.J., Williamson O.E., Williamson O.E., Winch G.M., Womack J., Womack J.   +29 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

STUDY ON VIBRATION CHARACTERISTICS OF THE POLYGON EFFECT OF SCRAPER CONVEYOR

Jixie qiangdu, 2018
Scraper conveyor chain and chain gear transmission as the research object,analysis of the scraper conveyor load and no-load conditions chain dynamics,and numerical simulation of the scraper conveyor special point chain speed and tension are simulated ...
ZHANG DongSheng, YU HaiYang, ZHAO XiBei, SONG ZhenDuo   +3 more
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