Results 71 to 80 of about 71,736 (261)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Progress on Preparation of Desiccants Used in Refrigerant System

open access: yesZhileng xuebao, 2006
The desiccants such as silica gel,active alumina,active carbon,and molecular sieve,are employed to purify the contaminations in the refrigerant system.With the development of new refrigerants,the properties of desiccants need to be improved.Based on the ...
王鹏飞   +4 more
doaj   +2 more sources

Quantum security analysis of Module-LWE PQC based on practical cost estimates

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
The security of lattice-based cryptography relies on the computational complexity of solving the Shortest Vector Problem (SVP) on a high-dimensional lattice. Due to its efficacy in addressing SVP, lattice-based cryptographic systems have so far used the
Seong-Min Cho   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Characterization of Mortar from Church Ruins in Barangay Budiao, Daraga, Albay

open access: yesMATEC Web of Conferences, 2018
The lack of information about the correct ways of restoring historical masonry materials from cultural heritage structures tends to create more damage to the said structures.
Mangay John Carlo A.   +4 more
doaj   +1 more source

Estimation of Chip Crushing Rate

open access: yesНаука и техника, 2003
In order to analyze chip crushing rate it is proposed to use a sieve analysis and methods of mathematical statistics which are applied in powder metallurgy, peat and coal industries and other branches. Estimation in fluctuation of chip size, stability of
E. M. Dechko
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

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