Results 71 to 80 of about 257,723 (287)

The Goldston-Pintz-Yildirim Sieve and Maximal Gaps

open access: yes, 2009
One field of particular interest in Number Theory concerns the gaps between consecutive primes. Within the last few years, very important results have been achieved on how small these gaps can be.
Seyalioglu, Hakan
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

STUDIES ON CONTINUOUS GRINDING PROCESS FOR DRIED WATER CHESTNUT KERNEL [PDF]

open access: yesJournal of Engineering Science and Technology, 2010
Grinding is a unit operation to break big solid material into smaller pieces. As far as process of grinding is concerned, power consumption, specific energy consumption and particle size distribution and mill capacity are main considerations from ...
S.K. GARG, U.C. LOHANI, J.P. PANDEY
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Preparation of NaA zeolite molecular sieve based on solid waste fly ash by high-speed dispersion homogenization-assisted alkali fusion-hydrothermal method and its performance of ammonia-nitrogen adsorption

open access: yesJournal of Science: Advanced Materials and Devices
A high-speed dispersion homogenization-assisted alkali fusion-hydrothermal method was successfully developed for the preparation of NaA zeolite molecular sieve with excellent adsorption performance for ammonia nitrogen using solid waste fly ash.
Guoqing Liu   +7 more
doaj   +1 more source

Comparative analysis ofthe functioning of sieve modulesforgrain cleaning machines [PDF]

open access: yesE3S Web of Conferences, 2019
Thearticlegives the calculationdiagrams of the sieve modules for grain cleaning machines whichallow to analyze the operation of the grain cleaning machines, and the trajectory of materials moving within the machine.
Butovchenko Andrey   +3 more
doaj   +1 more source

Use of the Micro-Deval Test for Assessing Alaska Aggregates [PDF]

open access: yes, 2012
INE/AUTC 12 ...
Liu, Juanyu   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Properties of the Sieve Bootstrap for Fractionally Integrated and Non-Invertible Processes [PDF]

open access: yes
In this paper we will investigate the consequences of applying the sieve bootstrap under regularity conditions that are sufficiently general to encompass both fractionally integrated and non-invertible processes.
D. S. Poskitt
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

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