Results 91 to 100 of about 17,918 (286)
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Ultrathin wide-angle large-area digital 3D holographic display using a non-periodic photon sieve
3D holographic displays still face many challenges such as small viewing angle and image size. Here the authors present a scalable method for displaying large holographic images with a wide viewing angle using a wide-angle diffracting element in a flat ...
Jongchan Park +2 more
doaj +1 more source
Sieve-element plastids and rbcL nucleotide sequences were analysed for Velloziaceae and all families sometimes discussed as close allies (Acanthochlamydaceae, Amaryllidaceae, Bromeliaceae, Cyclanthaceae, Haemodoraceae, Hypoxidaceae, Pandanaceae ...
Wink, M +6 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Determination of the Period of the Formation and Size of Sieve Element Area and Sieve Pore [PDF]
During the phloem development from parenchyma cells in a suspension culture of Streptanthus induced sucrose carrier and glucose carrier disappeared. Sieve element area and sieve pore induced suspension culture of Streptanthus were formed almost at the last period of the synthesis of sieve endoplasmic reticulum (SER) and p-protein.
openaire +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Distribution and Evolution of Forms and Types of Sieve-element Plastids in the Dicotyledons
Sieve-element plastids may contain any combination of protein crystals (c), protein filaments (f), and starch grains (s), or none of these. All structurally distinct combinations (=forms) possible (s, cs, cfs, c, cf, fs, f, o) are recorded among the 2100
Dietmar Behnke, Behnke, Dietmar
core +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Sieving Performance of Dual-Track Shale Shaker Based on DEM-MBD Coupling
To improve the processing capacity of the shale shaker, meet the needs of different working conditions in the drilling process, and solve the problems of “screen blinding” and “mud runaway” occurring in the existing shale shaker, a “linear + variable ...
Lü Zhipeng +4 more
doaj +1 more source

