Results 51 to 60 of about 99,408 (270)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Stress analysis and optimization of coarse aggregate of large stone porous asphalt mixture based on discrete element method

Case Studies in Construction Materials, 2023
The content of fine aggregate and asphalt in large stone porous asphalt mixture (LSPM) is low, and the load is mainly borne by the stable skeleton structure formed by the interlocking between coarse aggregates.
Zhaocheng Li, Dongdong Han, Yongli Zhao
doaj   +1 more source

Streaming Robust Submodular Maximization: A Partitioned Thresholding Approach [PDF]

, 2017
We study the classical problem of maximizing a monotone submodular function subject to a cardinality constraint k, with two additional twists: (i) elements arrive in a streaming fashion, and (ii) m items from the algorithm's memory are removed after the ...
Bogunovic, Ilija, Cevher, Volkan, Mitrović, Slobodan, Norouzi-Fard, Ashkan, Tarnawski, Jakub   +4 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Role of the phloem in the biochemistry and ecophysiology of benzylisoquinoline alkaloid metabolism

Frontiers in Plant Science, 2013
Benzylisoquinoline alkaloids (BIAs) are a diverse group of biologically active specialized metabolites produced mainly in four plant families. BIA metabolism is likely of monophyletic origin and involves multiple enzymes yielding structurally diverse ...
Eun-Jeong eLee, Jillian eHagel, Peter eFacchini   +2 more
doaj   +1 more source

Optimization of airflow cylinder sieve for threshed rice separation using CFD-DEM

Engineering Applications of Computational Fluid Mechanics, 2020
The airflow cylinder sieve directly affects the harvesting effect as one of the main components of the rice combine harvester. The process of grain separated from threshed rice mixture is a multi-physical random pattern. This paper constructed accurately
Jianbo Yuan, Hua Li, Xindan Qi, Tong Hu, Mingchao Bai, Yongjian Wang   +5 more
doaj   +1 more source

Study on matching optimization of screening efficiency and screen surface wear of flip screen

Meitan kexue jishu, 2023
In order to improve the production efficiency of the coal washing process, increase the service life of the washing equipment, maximize the potential production capacity of the screening equipment in the coal preparation plant, improve the rationality of
Yongli ZHOU, Jun MAO, Miao XIE, Longfei WU, Yun ZHU, Qingshuang MENG   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Electrophysiological approach to determine kinetic parameters of sucrose uptake by single sieve elements or phloem parenchyma cells in intact Vicia faba plants

Frontiers in Plant Science, 2013
Apart from a few using cut aphid stylets, no attempts have been made thus far to measure in vivo sucrose-uptake properties of sieve elements. We investigated the kinetics of sucrose uptake by single sieve elements and phloem parenchyma cells in Vicia ...
Jens B. Hafke, Sabina-Roxana eHöll, Christina eKühn, Aart J.E. Van Bel   +3 more
doaj   +1 more source