Results 61 to 70 of about 99,408 (270)
Foliar Phenotypic Plasticity Reflects Adaptation to Environmental Variability
Arabidopsis thaliana ecotypes adapted to native habitats with different daylengths, temperatures, and precipitation were grown experimentally under seven combinations of light intensity and leaf temperature to assess their acclimatory phenotypic ...
William W. Adams +5 more
doaj +1 more source
Sugar Coating the Phloem Sieve Element Wall [PDF]
Whereas fluorescent tagging of proteins has dramatically advanced the study of protein function in cell biology, similar approaches with walls have been difficult due to the few methods available to visualize polysaccharides and monitor their dynamic modifications.
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural and functional heterogeneity in phloem loading and transport
The phloem is often regarded as a relatively straightforward transport system composed of loading (collection), long-distance (transport) and unloading zones.
Thomas L. Slewinski +2 more
doaj +1 more source
Sieve-element differentiation and phloem sap contamination
Sieve elements (SEs) degrade selected organelles and cytoplasmic structures when they differentiate. According to classical investigations, only smooth ER, mitochondria, sieve element plastids, and, in most cases, P-proteins remain in mature SEs. More recent proteomics and immuno-histochemical studies, however, suggested that additional components ...
Michael, Knoblauch +4 more
openaire +3 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Resin-embedded Thin-section Immunohistochemistry Coupled with Triple Cellular Counterstaining
This protocol was developed to study protein localisation within the vascular bundles of developing tomato fruit however, it can be applied to any resin embedded plant tissue.
William Palmer +2 more
doaj +1 more source
Topos theory and `neo-realist' quantum theory
Topos theory, a branch of category theory, has been proposed as mathematical basis for the formulation of physical theories. In this article, we give a brief introduction to this approach, emphasising the logical aspects.
A. Döring +20 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

