Results 71 to 80 of about 8,279 (219)

Kinetics of Antibody Responses and Effector Cell Sensitivity After High Dose Birch Extract Nasal Challenge

open access: yesAllergy, EarlyView.
High‐dose birch‐extract nasal challenge induced synchronous peaks at 4 weeks in serum specific IgE (sIgE) and basophil sensitivity. Mast cell sensitivity via tSPT and sIgG1 and sIgG4 responses peaked later, at 6–8 weeks. Preseasonal allergen exposure attenuated seasonal sIgE increase and prevented further rise in tSPT sensitivity.
N. J. Campion   +18 more
wiley   +1 more source

IgE Antibody Function and Mast Cell Activation to Egg in Children Undergoing Baked and Loosely Cooked Egg Challenges

open access: yesAllergy, EarlyView.
MAT is dependent on the presence of allergen‐specific IgE and can provide false‐negative results in allergic patients with low allergen‐specific IgE levels. MAT and BAT are moderately correlated. MAT can be used as a surrogate of BAT, when fresh blood is not available or in the case of patients with non‐releaser basophils.
Vikki Houghton   +6 more
wiley   +1 more source

Noise Parameter Analysis of SiGe HBTs for Different Sizes in the Breakdown Region

open access: yesActive and Passive Electronic Components, 2016
Noise parameters of silicon germanium (SiGe) heterojunction bipolar transistors (HBTs) for different sizes are investigated in the breakdown region for the first time.
Chie-In Lee, Yan-Ting Lin, Wei-Cheng Lin
doaj   +1 more source

Preventive Application of House Dust Mite‐Sublingual Immunotherapy Induces Blocking Antibodies in Sensitized Preschool Children

open access: yesAllergy, EarlyView.
HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi   +12 more
wiley   +1 more source

Structure of the SigE regulatory network in Mycobacterium tuberculosis

open access: yesFrontiers in Microbiology
SigE is one of the main regulators of mycobacterial stress response and is characterized by a complex regulatory network based on two pathways, which have been partially characterized in conditions of surface stress.
Laura Cioetto-Mazzabò   +6 more
doaj   +1 more source

Natural History of Alternaria Sensitisation and Association With Asthma and Rhinitis From Childhood to Adulthood

open access: yesAllergy, EarlyView.
We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...
Mohammad Leily   +7 more
wiley   +1 more source

Determinants of Poor Health‐Related Quality of Life in Patients With Food Allergy

open access: yesAllergy, EarlyView.
Machine‐learning analysis of 502 well‐characterised food‐allergic patients was used to identify key determinants of poor FA‐HRQL, defined as FAQLQ ≥ 5. The most relevant predictors were adult age, female sex, multiple food allergies, severe reactions, need for urgent care, onset before 18 years, and longer disease duration.
Rosialzira Natasha Vera‐Berrios   +24 more
wiley   +1 more source

Tropomyosin-based cross-reactivity and asymptomatic shellfish sensitization in patients with perennial allergy

open access: yesFrontiers in Allergy
BackgroundMite, cockroach, and shellfish (crab, clam, and shrimp) proteins share allergenic epitopes. The determination of specific IgE (sIgE) against cockroach (Blattella germanica, relevant in asthma) and shellfish allergens (relevant in food allergy ...
Moritz Maximilian Hollstein   +7 more
doaj   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

open access: yesAllergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura   +7 more
wiley   +1 more source

Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations

open access: yesAllergy, EarlyView.
Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal   +42 more
wiley   +1 more source

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