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A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi   +5 more
wiley   +1 more source

Albumin Restores Endothelial Cell Mitochondrial Morphology in Patients With Decompensated Cirrhosis. [PDF]

open access: yesLiver Int
Fischer SE   +5 more
europepmc   +1 more source

Salmonella enterica persister cells exhibit distinct susceptibility profiles following exposure to human serum and macrophages. [PDF]

open access: yesPLoS One
Rodrigues RL   +8 more
europepmc   +1 more source

Characterization of the Lipidome of Neurons in Mouse Brain Nuclei Using Imaging Mass Spectrometry. [PDF]

open access: yesAnal Chem
Huergo C   +5 more
europepmc   +1 more source
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Predicting thermophysical properties of dialkylimidazolium ionic liquids from sigma profiles

Journal of Molecular Liquids, 2021
Abstract We present a Support Vector Regression (SVR) machine learning framework for predicting the viscosity, ionic conductivity, and density of imidazolium ionic liquids (ILs) using a universal set of features extracted from COSMO-RS sigma profiles.
Oscar Nordness   +5 more
openaire   +3 more sources

Sigma-Profile Database for Using COSMO-Based Thermodynamic Methods

Industrial & Engineering Chemistry Research, 2006
Thermodynamic methods based on conductor-like screening models (COSMO) originated from the use of solvation thermodynamics and computational quantum mechanics. These methods rely on sigma profiles specific to each molecule. A sigma profile is the probability distribution of a molecular surface segment having a specific charge density.
Eric Mullins   +7 more
exaly   +6 more sources

Novel Sigma Receptor Ligands:  Synthesis and Biological Profile

Journal of Medicinal Chemistry, 2007
The aim of the present study was to investigate the biological profile of new substituted 1-phenyl-2-cyclopropylmethylamines. High affinity for both sigma subtypes was achieved when 4-phenylpiperidin-4-ol (4a-e) and 4-benzylpiperidine moieties were present (5a-e).
PREZZAVENTO, Orazio   +11 more
openaire   +4 more sources

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