Results 231 to 240 of about 452,071 (254)
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NPC 16377, a potent and selective sigma-ligand. II. Behavioral and neuroprotective profile.

The Journal of Pharmacology and Experimental Therapeutics, 1993
6-[6-(4-Hydroxypiperidinyl)hexyloxy]-3-methylflavone HCI, (NPC 16377), a potent and highly selective sigma-site ligand, was evaluated in tests predictive of antipsychotic and neuroprotective potential and for toxicity. Like haloperidol, clozapine and remoxipride, and the sigma-ligands BMY 14802, ifenprodil and rimcazole, NPC 16377 reversed amphetamine ...
D B, Clissold   +9 more
openaire   +2 more sources

[Atypical antipsychotic profiles of sigma receptor ligands].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2000
This is a review on the recent results of research on sigma-receptor antagonists. NE-100, a selective sigma1-receptor antagonist, shows improvement of abnormal behaviors and cognitive dysfunction induced by phencyclidine (PCP). However, NE-100 does not inhibit dopamine agonist-induced behaviors nor induces catalepsy.
openaire   +1 more source

New prediction methods for solubility parameters based on molecular sigma profiles using pharmaceutical materials

International Journal of Pharmaceutics, 2018
Solubility parameters have been applied extensively in the chemical and pharmaceutical sciences. Particularly attractive is calculation of solubility parameters based on chemical structure and recently, new in silico methods have been proposed. Thus, screening charge densities of molecular surfaces (i.e.
Andreas Niederquell   +2 more
openaire   +3 more sources

U.S. hospital culture profiles for better performance in patient safety, patient satisfaction, Six Sigma, and lean implementation

International Journal of Production Economics, 2021
Min Kyung Lee   +2 more
exaly  

Use of composition profiles near sigma phase for assessment of localized corrosion resistance in a duplex stainless steel

Calphad: Computer Coupling of Phase Diagrams and Thermochemistry, 2019
Rodrigo Magnabosco   +1 more
exaly  

446 PHARMACOKINETIC PROFILE OF A SELECTIVE SIGMA‐1 RECEPTOR ANTAGONIST (S1RA) IN HUMAN

European Journal of Pain Supplements, 2010
M. Escriche   +13 more
openaire   +1 more source

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