Results 11 to 20 of about 6,084 (222)

Claisen Rearrangement Toward Cyclic Compound on Different Organic Synthesis Methods: Short Review

Chempublish Journal, 2023
The synthesis of functional and complex organic compounds is majorly performed by the Claisen rearrangement method. Claisen rearrangement is one of [3,3] sigmatropic rearrangements, a complex method in the synthesis of organic compounds, where it is ...
Rizki Rachmad Saputra, Reny Rosalina, Dimas Pramudita, Oktavia Rahmi Wulandari, Yuneta Yuneta, Amanda Natania Gracia, Tina Sugiyani, Marsya Imelya   +7 more
doaj   +1 more source

Novel Vulgarin Derivatives: Chemical Transformation, In Silico and In Vitro Studies

Molecules, 2023
Vulgarin, an eudesmanolide sesquiterpene isolated from Artemisia judaica, was refluxed with iodine to produce two derivatives (1 and 2), which were purified and spectroscopically identified as naproxen methyl ester analogs.
Hanan G. Sary, Mohammed A. Khedr, Khaled Y. Orabi   +2 more
doaj   +1 more source

Deciphering the Molecular Mechanism of Intramolecular Reactions from the Perspective of Bonding Evolution Theory

Physchem, 2022
The molecular mechanisms of three intramolecular rearrangements (I, the rearrangement of allyloxycycloheptatriene to yield tricyclic ketones; II, the cycloaddition of a nitrone-alkene to render two tricyclic isoxazolidines; and III, the decomposition of ...
Abel Idrice Adjieufack, Juan Andrés, Mónica Oliva, Vicent Sixte Safont   +3 more
doaj   +1 more source

A General and Scalable Synthesis of Polysubstituted Indoles

Molecules, 2020
A consecutive 2-step synthesis of N-unprotected polysubstituted indoles bearing an electron-withdrawing group at the C-3 position from readily available nitroarenes is reported.
David Tejedor, Raquel Diana-Rivero, Fernando García-Tellado   +2 more
doaj   +1 more source

4-(Aryl)-Benzo[4,5]imidazo[1,2-a]pyrimidine-3-Carbonitrile-Based Fluorophores: Povarov Reaction-Based Synthesis, Photophysical Studies, and DFT Calculations

Molecules, 2022
A series of novel 4-(aryl)-benzo[4,5]imidazo[1,2-a]pyrimidine-3-carbonitriles were obtained through the Povarov (aza-Diels–Alder) and oxidation reactions, starting from benzimidazole-2-arylimines.
Victor V. Fedotov, Maria I. Valieva, Olga S. Taniya, Semen V. Aminov, Mikhail A. Kharitonov, Alexander S. Novikov, Dmitry S. Kopchuk, Pavel A. Slepukhin, Grigory V. Zyryanov, Evgeny N. Ulomsky, Vladimir L. Rusinov, Valery N. Charushin   +11 more
doaj   +1 more source

Synthesis of 1,2-Dihydro-Substituted Aniline Analogues Involving N-Phenyl-3-aza-Cope Rearrangement Using a Metal-Free Catalytic Approach

Journal of Chemistry, 2020
An efficient metal-free domino reaction leading to structural/electronically divergent 1,2-dihydropyridines from easily accessible propargyl vinyl anilines via N-phenyl 3-aza-Cope sigmatropic rearrangement is reported with good to excellent yields using ...
Osamah Alduhaish, Ravi Varala, Syed Farooq Adil, Mujeeb Khan, Mohammed Rafiq H. Siddiqui, Abdulrhman AlWarthan, M. Mujahid Alam   +6 more
doaj   +1 more source

Claisen, Cope and Related Rearrangements in the Synthesis of Flavour and Fragrance Compounds

Molecules, 2000
A review of the use of the Claisen, Cope and related [3,3]-sigmatropic rearrangements, sequential ("tandem") sigmatropic rearrangements and the "ene" reaction in the syntheses of flavour and fragrance compounds is presented.
Janusz Nowicki
doaj   +1 more source

Possibility of [1,5] sigmatropic shifts in bicyclo[4.2.0]octa-2,4-dienes [PDF]

, 2015
The thermal equilibration of the methyl esters of endiandric acids D and E was subject to a computational study. An electrocyclic pathway via an electrocyclic ring opening followed by a ring flip and a subsequent electrocyclization proposed by Nicolaou ...
Catak, Saron, De Clercq, Pierre, Goossens, Hannelore, Hermosilla, Laura, Van Speybroeck, Veronique, Waroquier, Michel, Winne, Johan, Wouters, Sebastian   +7 more
core   +2 more sources

Recent advances in the total synthesis of agelastatins [PDF]

, 2010
Agelastatins represent an important family of marine alkaloids in terms of both exceptional biological activity and intriguing chemical structure.
Dong, Guangbin
core   +1 more source

Bifunctionalized Allenes. Part XIII. A Convenient and Efficient Method for Regioselective Synthesis of Phosphorylated α-Hydroxyallenes with Protected and Unprotected Hydroxy Group

Molecules, 2014
The paper describes a convenient and efficient method for regioselective synthesis of phosphorylated α-hydroxyallenes using an atom economical [2,3]-sigmatropic rearrangement of intermediate propargyl phosphites or phosphinites.
Ismail E. Ismailov, Ivaylo K. Ivanov, Valerij Ch. Christov   +2 more
doaj   +1 more source