Results 91 to 100 of about 6,175,859 (338)
Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits
Nature Communications, 2020 Metformin is an anti-diabetic drug that has shown promise to reduce M. tuberculosis susceptibility. Here the authors show that this effect is a result of metformin-mediated activation of anti-mycobacterial memory-like antigen-inexperienced CD8+CXCR3+ T ...
Julia Böhme +20 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
LinguisticsCorpus methods are now established within the field of signed language linguistics. Empirical investigations of signed language corpora have challenged many early assumptions about the nature of deaf community signed languages, while making us more aware
Puupponen Anna +7 more
doaj +1 more source
Simone Signoret 1921 - 1985: the star as sign - the sign as scar [PDF]
, 1995 1995-01 ...
core +1 more source
PLoS ONE, 2019 Background Vital signs, i.e. respiratory rate, oxygen saturation, pulse, blood pressure and temperature, are regarded as an essential part of monitoring hospitalized patients. Changes in vital signs prior to clinical deterioration are well documented and
I. Brekke +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A new framework for sign language recognition based on 3D handshape identification and linguistic modeling [PDF]
, 2014 Current approaches to sign recognition by computer generally have at least some of the following limitations: they rely on laboratory conditions for sign production, are limited to a small vocabulary, rely on 2D modeling (and therefore cannot deal with ...
Dilsizian, Mark +4 more
core
, 2018 The method of 1-bit ("sign-sign") random projections has been a popular tool for efficient search and machine learning on large datasets. Given two $D$-dim data vectors $u$, $v\in\mathbb{R}^D$, one can generate $x = \sum_{i=1}^D u_i r_i$, and $y = \sum_ ...
Li, Ping
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source