Results 101 to 110 of about 1,676,212 (286)

Kernel-Based Relevance Analysis with Enhanced Interpretability for Detection of Brain Activity Patterns

Frontiers in Neuroscience, 2017
We introduce Enhanced Kernel-based Relevance Analysis (EKRA) that aims to support the automatic identification of brain activity patterns using electroencephalographic recordings.
Andres M. Alvarez-Meza, Alvaro Orozco-Gutierrez, German Castellanos-Dominguez   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

EEG-Based Music Emotion Prediction Using Supervised Feature Extraction for MIDI Generation

Sensors
Advancements in music emotion prediction are driving AI-driven algorithmic composition, enabling the generation of complex melodies. However, bridging neural and auditory domains remains challenging due to the semantic gap between brain-derived low-level
Oscar Gomez-Morales, Hernan Perez-Nastar, Andrés Marino Álvarez-Meza, Héctor Torres-Cardona, Germán Castellanos-Dominguez   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Uncertainty-Aware Deep Learning for Robust and Interpretable MI EEG Using Channel Dropout and LayerCAM Integration

Applied Sciences
Motor Imagery (MI) classification plays a crucial role in enhancing the performance of brain–computer interface (BCI) systems, thereby enabling advanced neurorehabilitation and the development of intuitive brain-controlled technologies.
Óscar Wladimir Gómez-Morales, Sofia Escalante-Escobar, Diego Fabian Collazos-Huertas, Andrés Marino Álvarez-Meza, German Castellanos-Dominguez   +4 more
doaj   +1 more source

Automatic Ship Classification from Optical Aerial Images with Convolutional Neural Networks

Remote Sensing, 2018
The automatic classification of ships from aerial images is a considerable challenge. Previous works have usually applied image processing and computer vision techniques to extract meaningful features from visible spectrum images in order to use them as ...
Antonio-Javier Gallego, Antonio Pertusa, Pablo Gil   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source