Results 161 to 170 of about 1,664,025 (288)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Bioinspired flexible sensing-processing-visualizing integrated system towards tactile-visual signal recognition. [PDF]

Nat Commun
Wang Z, Lin J, Zhu Y, Sun R, Lin Q, Hu X, Sun J, Jiang Y, You K, Fu H, Guo X, Wang Y, Li D, Lin L, Li F, Liu Y, Zhao Y, Huang W.   +17 more
europepmc   +1 more source

Deep extreme learning machine with knowledge augmentation for EEG seizure signal recognition. [PDF]

Front Neuroinform, 2023
Zhang X, Dong S, Shen Q, Zhou J, Min J.
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Radio Frequency Signal Recognition of Unmanned Aerial Vehicle Based on Complex-Valued Convolutional Neural Network. [PDF]

Sensors (Basel)
Xin Y, Mu J, Jing X, Liu W.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A psycho-ecological signal recognition framework for user behavior prediction on digital media platforms. [PDF]

PLoS One
Xiong L, Li K, Wong WS.
europepmc   +1 more source

Structural basis of signal peptide recognition by the signal recognition particle [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2012
E. Sauer-Eriksson, S. Huang, G. Meriläinen, K. Brännström, T. Hainzl   +4 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Correction: Research on partial discharge signal recognition and classification of power transformer based on acoustic-VMD and CNN-LSTM. [PDF]

PLoS One
Chen L, Wen Y, Su H, Xiong K, Chen D.
europepmc   +1 more source