Results 141 to 150 of about 1,676,212 (286)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Signal recognition particle-dependent secretome in humans. [PDF]

Sci Rep
Miller SC, Tikhonova EB, Rodríguez-Almonacid CC, Bustamante C, Weintraub ST, Karamyshev AL.   +5 more
europepmc   +1 more source

Cross-subject emotion EEG signal recognition based on source microstate analysis. [PDF]

Front Neurosci, 2023
Zhang L, Xiao D, Guo X, Li F, Liang W, Zhou B.   +5 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Clinical Characteristics of Patients With Anti-Signal Recognition Particle Antibody: A Cohort Study. [PDF]

Immun Inflamm Dis
Jubber A, Durrani M, Almayahi A, Sunmboye K.   +3 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Temporal Regulation of Signal Recognition Particle During Translation. [PDF]

J Mol Biol
Qian R, Gora RJ, Chandrasekar S, Shan SO.   +3 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Signal Recognition Granule Receptor Beta Subunit Promotes Arrhythmogenic Remodeling in the Heart Failure Mice. [PDF]

J Am Heart Assoc
Zhang J, Pan Y, Gong Y, Kong B, Chen T, Shuai W, Huang H.   +6 more
europepmc   +1 more source

Application of Data Particle Geometrical Divide Algorithms in the Process of Radar Signal Recognition. [PDF]

Sensors (Basel), 2023
Dudczyk J, Rybak Ł.
europepmc   +1 more source