Results 141 to 150 of about 633,090 (317)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Crop Water Status Analysis from Complex Agricultural Data Using UMAP-Based Local Biplot

open access: yesRemote Sensing
To optimize growth and management, precision agriculture relies on a deep understanding of agricultural dynamics, particularly crop water status analysis.
Jenniffer Carolina Triana-Martinez   +4 more
doaj   +1 more source

Brain machine interface: motor imagery recognition with different signal length representations [PDF]

open access: yes, 2009
Link to publisher's homepage at http://ieeexplore.ieee.orgThis work investigates how signal representations affect the performance of a motor imagery recognition system, specifically we investigate on recognition accuracy and computational time of a ...
Paulraj, Murugesapandian   +4 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Recognition Memory is Fundamentally Continuous, and Strategic Discretization Does Not Change This [PDF]

open access: yes, 2019
Recognition memory research has long focused on whether it is mediated by discrete or continuous processes. Recent research has shown that the picture is more complex.
McAdoo, Ryan
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Robust Regularized Locality Preserving Indexing for Fiedler Vector Estimation

open access: yesIEEE Open Journal of Signal Processing
The Fiedler vector is the eigenvector associated with the algebraic connectivity of the graph Laplacian. It is central to graph analysis as it provides substantial information to learn the latent structure of a graph. In real-world applications, however,
Aylin Tastan   +2 more
doaj   +1 more source

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