Results 161 to 170 of about 3,807,942 (299)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Acoustic Signal Recognition of Partial Discharge Optical Fiber Sensors Using Time-Frequency Phase Composition. [PDF]

Sensors (Basel)
Jin X, Wang P, Guo P, Liu X, Wang Y.
europepmc   +1 more source

A signal recognition particle receptor gene from the sea cucumber, Apostichopus japonicas. [PDF]

Sci Rep, 2023
Zhang J, Sun Z, Su W, Wang Z, Meng W, Chang Y.   +5 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Clinical Characteristics of Patients With Anti-Signal Recognition Particle Antibody: A Cohort Study. [PDF]

Immun Inflamm Dis
Jubber A, Durrani M, Almayahi A, Sunmboye K.   +3 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Temporal Regulation of Signal Recognition Particle During Translation. [PDF]

J Mol Biol
Qian R, Gora RJ, Chandrasekar S, Shan SO.   +3 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Note recognition in polyphonic music using neural networks [PDF]

This report describes the initial results of work toward the development of a system for the automatic transcription of polyphonic musical works where the input to the system is a digital sound waveform representation (such as the data stored on a ...
Shuttleworth, T., Wilson, Roland
core  

Signal Recognition Granule Receptor Beta Subunit Promotes Arrhythmogenic Remodeling in the Heart Failure Mice. [PDF]

J Am Heart Assoc
Zhang J, Pan Y, Gong Y, Kong B, Chen T, Shuai W, Huang H.   +6 more
europepmc   +1 more source