Results 231 to 240 of about 1,676,212 (286)
Efficient FPGA Implementation of Convolutional Neural Networks and Long Short-Term Memory for Radar Emitter Signal Recognition. [PDF]
Sensors (Basel)Wu B +5 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Rheumatoid Arthritis Associated With Anti-Signal Recognition Particle Immune-Mediated Necrotizing Myopathy: A Case Report. [PDF]
J Investig Med High Impact Case RepBelkhribchia MR +6 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Immune-Mediated Necrotizing Myopathy Associated With Anti-signal Recognition Particle Antibody Complicated With Acute Respiratory Distress Syndrome: A Report of Two Cases. [PDF]
CureusFang DW, Chen YM.
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The Signal Recognition Particle
Annual Review of Biochemistry, 2001▪ Abstract The signal recognition particle (SRP) and its membrane-associated receptor (SR) catalyze targeting of nascent secretory and membrane proteins to the protein translocation apparatus of the cell. Components of the SRP pathway and salient features of the molecular mechanism of SRP-dependent protein targeting are conserved in all three ...
R J, Keenan +3 more
openaire +2 more sources
Structural basis of signal-sequence recognition by the signal recognition particle
Nature Structural & Molecular Biology, 2011The signal recognition particle (SRP) recognizes and binds the signal sequence of nascent proteins as they emerge from the ribosome. We present here the 3.0-Å structure of a signal sequence bound to the Methanococcus jannaschii SRP core. Structural comparison with the free SRP core shows that signal-sequence binding induces formation of the GM-linker ...
Tobias, Hainzl +4 more
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Recognition of translational termination signals
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1987Ribosomes can specifically shift at certain codons so that the mRNA is read in two different reading frames. To determine if frameshifting occurs at the level of termination, polymers of defined sequence containing AUG, a coding sequence and an in- or out-of-phase nonsense codon were used to bind a termination substrate or to program synthesis and ...
K, Buckingham +3 more
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A neuroelectric signal recognition system
Electroencephalography and Clinical Neurophysiology, 1972Abstract A neuroelectric signal recognition program written for a DEC PDP-12 digital computer is described. Unit selections are made on the basis of the minimal mean square amplitude differences between the incoming displayed signal and previous “template unit” selections. These templates are continuously being replaced by the incoming “units of best
V J, Prochazka, B, Conrad, F, Sindermann
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