Results 261 to 270 of about 633,090 (317)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Efficient FPGA Implementation of Convolutional Neural Networks and Long Short-Term Memory for Radar Emitter Signal Recognition. [PDF]

Sensors (Basel)
Wu B, Wu X, Li P, Gao Y, Si J, Al-Dhahir N.   +5 more
europepmc   +1 more source

Rheumatoid Arthritis Associated With Anti-Signal Recognition Particle Immune-Mediated Necrotizing Myopathy: A Case Report. [PDF]

J Investig Med High Impact Case Rep
Belkhribchia MR, Lobrinus JA, Semlil L, Chauveau N, Ajrinija A, Egervari K, Ennhaili ZE.   +6 more
europepmc   +1 more source

Immune-Mediated Necrotizing Myopathy Associated With Anti-signal Recognition Particle Antibody Complicated With Acute Respiratory Distress Syndrome: A Report of Two Cases. [PDF]

Cureus
Fang DW, Chen YM.
europepmc   +1 more source

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The Signal Recognition Particle

Annual Review of Biochemistry, 2001
▪ Abstract  The signal recognition particle (SRP) and its membrane-associated receptor (SR) catalyze targeting of nascent secretory and membrane proteins to the protein translocation apparatus of the cell. Components of the SRP pathway and salient features of the molecular mechanism of SRP-dependent protein targeting are conserved in all three ...
R J, Keenan, D M, Freymann, R M, Stroud, P, Walter   +3 more
openaire   +2 more sources

Structural basis of signal-sequence recognition by the signal recognition particle

Nature Structural & Molecular Biology, 2011
The signal recognition particle (SRP) recognizes and binds the signal sequence of nascent proteins as they emerge from the ribosome. We present here the 3.0-Å structure of a signal sequence bound to the Methanococcus jannaschii SRP core. Structural comparison with the free SRP core shows that signal-sequence binding induces formation of the GM-linker ...
Tobias, Hainzl, Shenghua, Huang, Gitte, Meriläinen, Kristoffer, Brännström, A Elisabeth, Sauer-Eriksson   +4 more
openaire   +2 more sources

New Insights into Signal Recognition and Elongation Arrest Activities of the Signal Recognition Particle

Biological Chemistry, 1999
AbstractThe signal recognition particle (SRP), a ubiquitous cytoplasmic ribonucleoprotein particle, plays an essential role in promoting co-translational translocation of proteins into the endoplasmic reticulum. Here, we summarise recent progress made in the understanding of two essential SRP functions: the signal recognition function, which ensures ...
Bui, Nazarena, Strub, Katharina
openaire   +2 more sources

EEG signals for emotion recognition

Journal of Computational Methods in Sciences and Engineering, 2010
This paper proposes an emotion recognition system using the electroencephalographic (EEG) signals. Both time domain and frequency domain approaches for feature extraction were evaluated using neural network (NN) and fuzzy neural network (FNN) as classifiers. Data was collected using psychological stimulation experiments.
Abdul Wahab 0001, Norhaslinda Kamaruddin, Lavan Palaniappan, Ma Li, Reza Khosrowabadi   +4 more
openaire   +2 more sources