Results 101 to 110 of about 256,514 (313)

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

Linear Invariant Systems Theory for Signal Enhancement

open access: yes, 2011
This paper discusses a linear time invariant (LTI) systems approach to signal enhancement via projective subspace techniques. It provides closed form expressions for the frequency response of data adaptive finite impulse response eigenfilters.
Lang, Elmar W.   +5 more
core  

Reconstruction of compressed signals for bridge structures based on autoregressive iterations

open access: yesJixie qiangdu
ObjectiveThe vibration signals of bridge structures under ambient excitation usually present low signal-to-noise ratio and poor sparsity, which makes it difficult to realize high-precision compressed sensing.
LI Cui   +3 more
doaj  

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Exact reconstruction formulas for oversampled processes with missing samples

open access: yes, 2009
La reconstruction d'un signal à bande limitée à partir d'échantillons peut être réalisé avec une période d'échantillonnage de 1 si le spectre du signal a un support inférieur à 2 pi.
LACAZE, Bernard, THOMAS, Nathalie
core  

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

A Hierarchical Bayesian Model for Frame Representation [PDF]

open access: yes, 2010
In many signal processing problems, it is fruitful to represent the signal under study in a frame. If a probabilistic approach is adopted, it becomes then necessary to estimate the hyperparameters characterizing the probability distribution of the frame
Amel Benazza-Benyahia   +9 more
core   +1 more source

Response probability density of a system with cross-correlated parametric and additive input noises

open access: yesApplied and Computational Mechanics, 2019
Data processing and subsequent mining is a widely followed task. Employment of suitable evaluation and interpretation procedures can significantly improve the effective resolution of measuring facility using an identical hardware equipment.
Nárstek J., Fischer C.
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran   +13 more
wiley   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree   +9 more
wiley   +1 more source

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