Results 101 to 110 of about 424,960 (245)

Faculty Opinions recommendation of Engineering a signal transduction mechanism for protein-based biosensors.

, 2005
Jeffery G. Saven
openalex   +2 more sources

A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy. [PDF]

, 1998
J.B. Pracyk, K Tanaka, Donald D. Hegland, Kyo Sang Kim, R Sethi, Ilsa I. Rovira, D R Blazina, L Lee, J T Bruder, Imre Kovesdi, Pascal J Goldshmidt‐Clermont, Kaikobad Irani, Toren Finkel   +12 more
openalex   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Smad1/5 signal transduction regulates the ameloblastic differentiation of induced pluripotent stem cells

, 2020
Zhi Liu, Guang Zeng, Qing Qin, Cong SUN, Lei Tan   +4 more
openalex   +1 more source

Frequent Interpersonal Stress and Inflammatory Reactivity Predict Depressive-Symptom Increases: Two Tests of the Social-Signal-Transduction Theory of Depression

, 2021
Annelise A. Madison, Rebecca Andridge, M. Rosie Shrout, Megan E. Renna, Jeanette M. Bennett, Lisa M. Jaremka, Christopher P. Fagundes, Martha A. Belury, William B. Malarkey, Janice K. Kiecolt‐Glaser   +9 more
openalex   +2 more sources

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Signal transduction pathways involved in inhibition of axonal regeneration after CNS injury

, 2017
Ezgi Öztürk
openalex   +1 more source

T‐cell signal transduction in children with cow's milk allergy – increased MAP kinase activation in patients with acute symptoms of cow's milk allergy [PDF]

, 2003
Pamela Österlund, Maria von Willebrand, Leif C. Andersson, Hanna Suomalainen   +3 more
openalex   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source