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CD4 and Signal Transduction

1996
The CD4 molecule plays an important role in the development of CD4+T lymphocytes and it also acts as a coreceptor to enhance responses mediated via the TCR. It is now established that CD4 functions both as an adhesion molecule favoring the T cell: APC interaction and as a signaling molecule.
K S, Ravichandran   +2 more
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Sulfonylurea Signal Transduction

1991
In the pancreatic beta cells the proximal step in sulfonylurea signal transduction is the binding of these clinically important drugs to high-affinity receptors in the beta cell membrane. Using HIT cells as a model system, we have established an extremely close correlation between the affinity of binding of glyburide and its analog, iodoglyburide, and ...
A E, Boyd   +9 more
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Signal transduction in photoreceptors

Biochemical Society Transactions, 1991
The biochemical role of the visual-pigment protein, rhodopsin, is reviewed, with reference to vertebrate rods and cones and the microvillar photoreceptors of invertebrates. New results are presented on the structure of squid rhodopsin, which possesses an extensive proline-rich repeat at its C-terminus, using negative-stain electron microscopy.
K, Langmack, H, Saibil
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ABA signal transduction

Current Opinion in Plant Biology, 1998
Recent advances in the study of abscisic acid signal transduction include the identification of cyclic ADP-ribose as a central mediator of abscisic acid responses. The characterisation of type 2C protein phosphatases, ABI1 and ABI2, implicates negative control and redundant action on the signal pathway of this hormone.
E, Grill, A, Himmelbach
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Lymphokine signal transduction

Cellular Signalling, 1990
Lymphokines are a group of signalling molecules involved in communication between cells, mainly those of the immune system. The lymphokines are multi-functional and most of them have mitogenic or co-mitogenic activity. An understanding of lymphokine biology is essential to understand how the immune system develops and functions and to provide a ...
Guy, G.R., Bee, N.G.S., Peng, C.S.
openaire   +3 more sources

Phosphoinositides and signal transduction

Cellular and Molecular Life Sciences, 2002
Phosphoinositides comprise a family of eight minor membrane lipids which play important roles in many signal transducing pathways in the cell. Signaling through various phosphoinositides has been shown to mediate cell growth and proliferation, apoptosis, cytoskeletal changes, insulin action and vesicle trafficking.
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Signal Transduction in Aspergilli

2007
International ...
Yu, J., D'Enfert, Christophe
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KIT SIGNAL TRANSDUCTION

Hematology/Oncology Clinics of North America, 2000
The current understanding of kit signaling is that a limited number of signaling proteins interact to build multiple interacting networks that allow diverse cellular responses. Cytoplasmic signaling proteins are increasingly seen to form networks directed through converging and interacting pathways rather than following a simple linear model. There are
M L, Taylor, D D, Metcalfe
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Signal transduction in bacteria

Nature, 1990
Cells display a remarkable ability to respond to small fluctuations in their surroundings. In simple microbial systems, information from sensory receptors feeds into a circuitry of regulatory proteins that transfer high energy phosphoryl groups from histidine to aspartate side chains.
J B, Stock, A M, Stock, J M, Mottonen
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Auxin signal transduction

Essays in Biochemistry, 2015
The plant hormone auxin (indole-3-acetic acid, IAA) controls growth and developmental responses throughout the life of a plant. A combination of molecular, genetic and biochemical approaches has identified several key components involved in auxin signal transduction.
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