Results 31 to 40 of about 1,096,363 (351)

Identification of Scopoletin and Chlorogenic Acid as Potential Active Components in Sunflower Calathide Enzymatically Hydrolyzed Extract towards Hyperuricemia

open access: yesApplied Sciences, 2021
It is known that sunflower (Helianthus annuus L.) calathide enzymatically hydrolyzed extract (SCHE) contributes to the regulation of serum uric acid (UA); however, evidence regarding its bioactive components and mechanism are lacking.
Huining Dai   +3 more
doaj   +1 more source

Self-organization of signal transduction

open access: yes, 2013
We propose a model of parameter learning for signal transduction, where the objective function is defined by signal transmission efficiency. We apply this to learn kinetic rates as a form of evolutionary learning, and look for parameters which satisfy ...
Scheler, Gabriele
core   +2 more sources

Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer

open access: yesNature Communications, 2018
How tumor cells control metastatic niche formation is not fully understood. Here, the authors show in a lung metastatic niche, high-metastatic hepatocellular carcinoma cells secrete exosomal miR-1247-3p that leads to activation of β1-integrin-NF ...
Tian Fang   +15 more
doaj   +1 more source

Finite-State Channel Models for Signal Transduction in Neural Systems

open access: yes, 2016
Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes.
Eckford, Andrew W.   +2 more
core   +1 more source

Global, quantitative and dynamic mapping of protein subcellular localization

open access: yeseLife, 2016
Subcellular localization critically influences protein function, and cells control protein localization to regulate biological processes. We have developed and applied Dynamic Organellar Maps, a proteomic method that allows global mapping of protein ...
Daniel N Itzhak   +3 more
doaj   +1 more source

Serotonin-promoted elevation of ROS levels may lead to cardiac pathologies in diabetic rat [PDF]

open access: yesArchives of Biological Sciences, 2015
Patients with diabetes mellitus (DM) develop tendencies toward heart disease. Hyperglycemia induces the release of serotonin from enterochromaffin cells (EC).
Ali Tahir   +6 more
doaj   +1 more source

Fold-Hopf Bursting in a Model for Calcium Signal Transduction

open access: yes, 2002
We study a recent model for calcium signal transduction. This model displays spiking, bursting and chaotic oscillations in accordance with experimental results. We calculate bifurcation diagrams and study the bursting behaviour in detail.
Brusch, Lutz   +4 more
core   +1 more source

Impact of sorbic acid on germinant receptor-dependent and -independent germination pathways in Bacillus cereus [PDF]

open access: yes, 2011
Amino acid- and inosine-induced germination of Bacillus cereus ATCC 14579 spores was reversibly inhibited in the presence of 3 mM undissociated sorbic acid. Exposure to high hydrostatic pressure, Ca-dipicolinic acid (DPA), and bryostatin, an activator of
Abee, T.   +2 more
core   +2 more sources

Oxygen Signal Transduction [PDF]

open access: yesIUBMB Life, 2001
AbstractAlthough manifestations of O 2 adaptation have long been examined, only now are biochemical mechanisms of O 2 regulation beginning to be understood. This article comments on the current state of knowledge about proteins that function as direct sensors of molecular oxygen and makes predictions about as yet undiscovered sensors.
openaire   +3 more sources

Optimal length and signal amplification in weakly activated signal transduction cascades

open access: yes, 2003
Weakly activated signaling cascades can be modeled as linear systems. The input-to-output transfer function and the internal gain of a linear system, provide natural measures for the propagation of the input signal down the cascade and for the ...
Chaves, Madalena   +2 more
core   +2 more sources

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